Background Osteosarcoma is a common primary malignant tumour of the bone that usually
occurs in children and adolescents. It is characterised by difficult treatment, recurrence and …

Osteosarcoma (OS) is a bone cancer mostly occurring in pediatric population. Current
treatment regime of surgery and intensive chemotherapy could cure about 60%–75 …

Osteosarcoma is a relatively uncommon cancer, accounting for 5% of childhood cancers
and 8.9% of cancer-related deaths in children. The overall incidence is five cases per million …

Improving the survival of patients with osteosarcoma has long proved challenging, although
the treatment of this disease is on the precipice of advancement. The increasing feasibility of …

Osteosarcoma is the most common primary tumor of bone. Approximately 2/3 of patients
who present with localized osteosarcoma can be expected to be cured of their disease with …

Osteosarcoma (OS) is a highly malignant tumor occurring in bone tissue with a high
propensity to metastasize, and its underlying mechanisms remain largely elusive. The OS …

Osteosarcoma (OS) is a class of cancer originating from bone, mainly afflicting children or
young adults. It is the second highest cause of cancer-related death in these age groups …

Introduction: Current treatment of osteosarcoma includes surgical resection of all gross
disease in conjunction with systemic chemotherapy to control micro-metastatic disease. This …

Osteosarcoma, a highly malignant tumor, is characterized by widespread and recurrent
chromosomal and genetic abnormalities. In recent years, a number of elaborated …

Introduction: Osteosarcoma (OS), the most common primary malignant bone tumor, is
currently treated with pre-and postoperative chemotherapy in association with the surgical …