Abstract Purpose of Review This article gives a brief overview of the most recent
developments in osteosarcoma treatment, including targeting of signaling pathways …

Osteosarcoma treatment follows very simple rules: if you want a cure, cut out all detectable
tumour and poison invisible tumour cells with as much chemotherapy as the patient can …

Osteosarcoma is the most common primary malignant bone tumor in children and young
adults. The standard-of-care curative treatment for osteosarcoma utilizes doxorubicin …

Simple Summary Osteosarcoma is the most common malignant bone tumor in children, with
a 5-year survival rate ranging from 70% to 20% depending on the aggressiveness of the …

Osteosarcoma is the most common malignant primary bone tumor in children and
adolescents. Current optimal treatment for osteosarcoma consists of multi-agent …

Osteosarcoma is an aggressive cancer in skeletal system with unknown molecular
mechanisms of etiology and pathogenesis, therefore it remains a challenge for current …

Targeted therapy for osteosarcoma includes organ, cell and molecular biological targeting;
of these, organ targeting is the most mature. Bone‐targeted drug delivery systems are used …

Osteosarcoma, the most common type of primary malignant tumour that develops in bone,
can be classified into several different sub-types. While the majority of osteosarcomas are …

Osteosarcoma (OS) is the most common primary malignant bone tumor, which usually
occurs in children and adolescents. It is generally a high-grade malignancy presenting with …

High-grade osteosarcomas are the most common primary malignant tumors of bone. With
complete surgical resection and multi-agent chemotherapy up to 70% of patients with high …