Osteosarcoma is a primary bone malignancy generally affecting the young, with 60% of
cases occurring before the age of 25 years and the peak incidence at 15 years. Survival has …

Patients who are newly diagnosed with osteosarcoma face a daunting year of medical and
surgical therapy, often filled with hospitalizations and changes in lifestyle. Fortunately, the …

Background The objective of this study is to explore the off-label use of targeted therapies
(TTs) for patients with osteosarcoma registered within the French Sarcoma Group–Bone …

Since osteosarcoma (OS) is an aggressive bone cancer with unknown molecular pathways
of etiology and pathophysiology, improving patient survival has long been a challenge. The …

Osteosarcoma is the most common primary bone tumor in childhood and adolescence. The
use of combination chemotherapy and surgery enables long-term survival in approximately …

Osteosarcoma (OS) is the most common primary malignant bone tumor that more commonly
occurs in children and adolescents. The most commonly used treatment for OS is surgery …

Osteosarcoma Osteosarcoma, which is most common in people 10 to 30 years of age, is
generally treated with resection and adjuvant chemotherapy. Detection of gene …

Introduction: Current treatment of conventional and non-conventional high-grade
osteosarcoma (HGOS) is based on the surgical removal of primary tumor and, when …

The current management of osteosarcoma (OS) is critically reviewed and a modified
treatment strategy is put forward for discussion. The overall treatment results in high-grade …

Bone sarcoma is a rare component of malignant solid tumors that accounts for only~ 0.2% of
malignancies. Bone sarcomas present various histological types, and genomic mutations …