Dry powder inhalers for pulmonary drug delivery

HW Frijlink, AH De Boer - Expert opinion on drug delivery, 2004 - Taylor & Francis
The pulmonary route is an interesting route for drug administration, both for effective local
therapy (asthma, chronic obstructive pulmonary disease or cystic fibrosis) and for the …

How can we bring high drug doses to the lung?

S Claus, C Weiler, J Schiewe, W Friess - European Journal of …, 2014 - Elsevier
In the last decades, dry powder inhalation has become a very attractive option for pulmonary
drug delivery to treat lung diseases like cystic fibroses and lung infections. In contrast to the …

Dry powder formulations for pulmonary delivery

RJ Malcolmson, JK Embleton - Pharmaceutical Science & Technology …, 1998 - Elsevier
This review examines the key issues surrounding the development and preparation of
formulations for dry powder inhalers. The various inhaler devices that are currently available …

Dry powder inhalers: an overview

PJ Atkins - Respiratory care, 2005 - rc.rcjournal.com
Dry powder inhalers (DPIs) are a widely accepted inhaled delivery dosage form, particularly
in Europe, where they currently are used by a large number of patients for the delivery of …

Dry powder inhalers for optimal drug delivery

SP Newman - Expert opinion on biological therapy, 2004 - Taylor & Francis
Dry powder inhalers (DPIs) have been available for delivering drugs to the lungs for over 30
years. In the last decade there has been a big increase in DPI development, resulting partly …

Developing and advancing dry powder inhalation towards enhanced therapeutics

S Stegemann, S Kopp, G Borchard, VP Shah… - European journal of …, 2013 - Elsevier
Enhanced therapeutics are drug products derived from existing generic drugs that provide
additional benefits to the patients and the healthcare system. Enhanced therapeutics are …

Recent advances in capsule-based dry powder inhaler technology

F Lavorini, M Pistolesi, OS Usmani - Multidisciplinary respiratory medicine, 2017 - Springer
Pulmonary drug delivery is currently the focus of accelerated research and development
because of the potential to produce maximum therapeutic benefit to patients by directly …

Developing an efficient and reliable dry powder inhaler for pulmonary drug delivery–a review for multidisciplinary researchers

N Islam, MJ Cleary - Medical engineering & physics, 2012 - Elsevier
Pulmonary drug delivery is the focus of much research and development because of its
great potential to produce maximum therapeutic benefit. Among the available options the dry …

Devices for dry powder drug delivery to the lung

K Berkenfeld, A Lamprecht, JT McConville - Aaps Pharmscitech, 2015 - Springer
Dry powder inhalers (DPIs) are an important and increasingly investigated method of
modern therapy for a growing number of respiratory diseases. DPIs are a promising option …

Drug delivery to the respiratory tract using dry powder inhalers

MP Timsina, GP Martin, C Marriott, D Ganderton… - International journal of …, 1994 - Elsevier
The inhalation of aerosolised drug has become a well established treatment modality in
conditions such as asthma. The pressurised metered-dose inhaler (MDI) is still the most …