Mutations of the proteolipid protein (Plp) gene cause a generalized central nervous system
(CNS) myelin deficit in Pelizaeus‐Merzbacher disease of man and various tremor …

The transgenic mice, which were produced by introducing the wild type proteolipid protein
(PLP) gene, revealed different neurological symptoms depending on expressed gene …

The X chromosome‐linked PLP/DM‐20 gene is the CNS myelin gene most frequently
associated with mutations, resulting in dysmyelination in several species including man …

Proteolipid protein (PLP) is an integral membrane protein of CNS myelin. Mutations of the X
chromosome-linked PLP gene cause glial cell death and myelin deficiency in jimpy mice …

Mutations of the major myelin gene, proteolipid protein (Plp), cause Pelizaeus‐Merzbacher
disease and some forms of spastic paraplegia in man and dysmyelinating phenotypes in …

Pelizaeus-Merzbacher disease (PMD) is a dysmyelinating disease resulting from mutations,
deletions, or duplications of the proteolipid protein (PLP) gene. Distinguishing features of …

The two proteins, proteolipid protein and DM20, which are encoded by alternative transcripts
from the proteolipid protein (PLP) gene, are major components of central nervous system …

PMD (Pelizaeus–Merzbacher disease), a CNS (central nervous system) disease
characterized by shortened lifespan and severe neural dysfunction, is caused by mutations …

Proteolipid protein (PLP) and its smaller isoform DM20 constitute the major myelin proteins
of the CNS. Mutations of the X‐linked Plp gene cause the heterogeneous syndromes of …

Transgenic Lewis rats overexpressing proteolipid protein (PLP) genes in peripheral and
central nervous myelin were produced by microinjecting murine genomic PLP sequences …