Evaluation of the therapeutic efficacy of human bone marrow mesenchymal stem cells with COX-2 silence and TGF-β3 overexpression in rabbits with antigen-induced …

T He, S Sun - Experimental Cell Research, 2022 - Elsevier
Abstract Objective Mesenchymal stem cells (MSCs), especially genetically modified MSCs,
have become a promising therapeutic approach for the treatment of rheumatoid arthritis (RA) …

Cell therapy using allogeneic bone marrow mesenchymal stem cells prevents tissue damage in collagen‐induced arthritis

A Augello, R Tasso, SM Negrini… - Arthritis & …, 2007 - Wiley Online Library
Abstract Objective Mesenchymal stem cells (MSCs) are precursors of tissue of mesenchymal
origin, but they also have the capacity to regulate the immune response by suppressing T …

Transforming growth factor β–transduced mesenchymal stem cells ameliorate experimental autoimmune arthritis through reciprocal regulation of Treg/Th17 cells and …

MJ Park, HS Park, ML Cho, HJ Oh, YG Cho… - Arthritis & …, 2011 - Wiley Online Library
Objective Bone marrow–derived mesenchymal stem cells (MSCs) can prevent various
autoimmune diseases. We examined the therapeutic potential of transforming growth factor …

Treatment of collagen-induced arthritis using immune modulatory properties of human mesenchymal stem cells

KH Park, CH Mun, MI Kang, SW Lee… - Cell …, 2016 - journals.sagepub.com
Mesenchymal stem cells (MSCs) have immune modulatory properties. We investigated the
potential therapeutic effects of human bone marrow (BM)-, adipose tissue (AD)-, and cord …

[HTML][HTML] Intraperitoneal infusion of mesenchymal stem cell attenuates severity of collagen antibody induced arthritis

Y Nam, SM Jung, YA Rim, H Jung, K Lee, N Park… - PLoS …, 2018 - journals.plos.org
It is unclear how systemic administration of mesenchymal stem cells (MSCs) controls local
inflammation. The aim of this study was to evaluate the therapeutic effects of human MSCs …

[HTML][HTML] Mesenchymal stem cells ameliorate experimental arthritis via expression of interleukin-1 receptor antagonist

K Lee, N Park, H Jung, YA Rim, Y Nam, J Lee, SH Park… - PloS one, 2018 - journals.plos.org
Human bone marrow-derived mesenchymal stem cells (MSCs) have been observed to
inhibit arthritis in experimental animal models such as collagen-induced arthritis. However …

Immunosuppressive effects of mesenchymal stem cells in collagen-induced mouse arthritis

F Mao, WR Xu, H Qian, W Zhu, YM Yan, QX Shao… - Inflammation …, 2010 - Springer
Objective The objective of this study was to investigate the efficacy of mesenchymal stem
cell (MSC) in the treatment of arthritis. Methods Mesenchymal stem cells were injected …

Reversal of the immunosuppressive properties of mesenchymal stem cells by tumor necrosis factor α in collagen‐induced arthritis

F Djouad, V Fritz, F Apparailly… - Arthritis & …, 2005 - Wiley Online Library
Objective Adult mesenchymal stem cells (MSCs) represent promising tools for therapeutic
applications such as tissue engineering and cellular therapy. Recent data suggest that, due …

Mesenchymal stem cells regulate the innate and adaptive immune responses dampening arthritis progression

RA Contreras, FE Figueroa, F Djouad… - Stem Cells …, 2016 - Wiley Online Library
Mesenchymal stem cells (MSCs) are multipotent stem cells that are able to immunomodulate
cells from both the innate and the adaptive immune systems promoting an anti‐inflammatory …

Intra‐articular injection of human synovial membrane‐derived mesenchymal stem cells in murine collagen‐induced arthritis: assessment of immunomodulatory …

M Yan, X Liu, Q Dang, H Huang, F Yang… - Stem cells …, 2017 - Wiley Online Library
The aim of this study was to evaluate the efficacy of human synovial membrane‐derived
MSCs (SM‐MSCs) in murine collagen‐induced arthritis (CIA). Male mice (age 7–9 weeks) …