Conditioned medium of IGF1-induced synovial membrane mesenchymal stem cells increases chondrogenic and chondroprotective markers in chondrocyte …
Recently, mesenchymal stem cells (MSCs) have been the most explored cells for cell
therapy for osteoarthritis (OA) that can be obtained from various sources. Synovial …
therapy for osteoarthritis (OA) that can be obtained from various sources. Synovial …
[HTML][HTML] Discrepancy between the in vitro and in vivoeffects of murine mesenchymal stem cells on T-cell proliferation and collagen-induced arthritis
E Schurgers, H Kelchtermans, T Mitera… - Arthritis research & …, 2010 - Springer
Introduction The goal of this study is to analyze the potential immunosuppressive properties
of mesenchymal stem cells (MSC) on T cell proliferation and in collagen-induced arthritis …
of mesenchymal stem cells (MSC) on T cell proliferation and in collagen-induced arthritis …
[HTML][HTML] Interleukin-17A-or tumor necrosis factor α-mediated increase in proliferation of T cells cocultured with synovium-derived mesenchymal stem cells in …
Z Zhang, Y Ding, W Li, B Song, R Yang - Arthritis research & therapy, 2013 - Springer
Abstract Introduction Mesenchymal stem cells (MSCs) represent promising applications in
rheumatoid arthritis (RA). However, the inflammatory niche in the RA synovium could …
rheumatoid arthritis (RA). However, the inflammatory niche in the RA synovium could …
Adoptive transfer of human gingiva‐derived mesenchymal stem cells ameliorates collagen‐induced arthritis via suppression of Th1 and Th17 cells and enhancement …
M Chen, W Su, X Lin, Z Guo, J Wang… - Arthritis & …, 2013 - Wiley Online Library
Objective Current approaches offer no cures for rheumatoid arthritis (RA). Accumulating
evidence has revealed that manipulation of bone marrow–derived mesenchymal stem cells …
evidence has revealed that manipulation of bone marrow–derived mesenchymal stem cells …
[HTML][HTML] Mesenchymal stem cells markedly suppress inflammatory bone destruction in rats with adjuvant-induced arthritis
T Takano, YJ Li, A Kukita, T Yamaza, Y Ayukawa… - Laboratory …, 2014 - Elsevier
Mesenchymal stem cells (MSCs) have potential to differentiate into multiple cell lineages.
Recently, it was shown that MSCs also have anti-inflammatory and immunomodulatory …
Recently, it was shown that MSCs also have anti-inflammatory and immunomodulatory …
[HTML][HTML] Allogeneic mesenchymal stem cells inhibited T follicular helper cell generation in rheumatoid arthritis
R Liu, X Li, Z Zhang, M Zhou, Y Sun, D Su, X Feng… - Scientific reports, 2015 - nature.com
T follicular helper (Tfh) cells provide help for antigen-specific B cells. We have previously
shown that Tfh cell frequency was increased and associated with auto-antibodies in patients …
shown that Tfh cell frequency was increased and associated with auto-antibodies in patients …
[HTML][HTML] Mesenchymal stem cells genetically engineered to express platelet-derived growth factor and heme oxygenase-1 ameliorate osteoarthritis in a canine model
J Oh, YS Son, WH Kim, OK Kwon, BJ Kang - Journal of Orthopaedic …, 2021 - Springer
Abstract Background Mesenchymal stem cells (MSCs) are used for the treatment of
osteoarthritis (OA), and MSC genetic engineering is expected to enhance cartilage repair …
osteoarthritis (OA), and MSC genetic engineering is expected to enhance cartilage repair …
[HTML][HTML] Mesenchymal stem cells in arthritis: role of bone marrow microenvironment
C Jorgensen - Arthritis research & therapy, 2010 - Springer
Based on their capacity to suppress immune responses, multipotent mesenchymal stromal
cells (MSCs) are intensively studied for regenerative medicine. Moreover, MSCs are potent …
cells (MSCs) are intensively studied for regenerative medicine. Moreover, MSCs are potent …
[HTML][HTML] Mesenchymal stem cells secrete factors that inhibit inflammatory processes in short-term osteoarthritic synovium and cartilage explant culture
GM Van Buul, E Villafuertes, PK Bos… - Osteoarthritis and …, 2012 - Elsevier
OBJECTIVE: Mesenchymal stem cells (MSCs) are promising candidates for osteoarthritis
(OA) therapies, although their mechanism of action remains unclear. MSCs have recently …
(OA) therapies, although their mechanism of action remains unclear. MSCs have recently …