OBJECTIVE: Mesenchymal stem cells (MSCs) are promising candidates for osteoarthritis
(OA) therapies, although their mechanism of action remains unclear. MSCs have recently …

Rheumatoid arthritis (RA) is an advanced autoimmune disease described by joint
involvement. The special properties of mesenchymal stem cells (MSCs) introduced them as …

OBJECTIVE: To investigate the relationship between the meniscal defect area and OA
progression and explore the effect and mechanism of SMSCs cell therapy in knee …

To compare human adipose tissue mesenchymal stem cells (AT-MSCs) and etanercept as
immunomodulatory agents for collagen-induced arthritis (CIA). CIA was induced by rats' …

Objective. Rheumatoid arthritis (RA) is a T-cell-mediated systematic disease and is usually
accompanied by articular cartilage damage. In the present study, we explored the effects of …

Background Despite recent advances in the treatment of arthritis with the development of
disease-modifying antirheumatic drugs, 30% of patients still fail to respond to treatment …

Mesenchymal stem cells (MSCs) possess immunomodulatory properties and have potential,
however, there have been conflicting reports regarding their effects in rheumatoid arthritis …

We evaluated the therapeutic potential of mesenchymal stem cell-conditioned medium (CM-
MSC) as an alternative to cell therapy in an antigen-induced model of arthritis (AIA). Disease …

Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by articular
destruction and functional loss. Methotrexate (MTX) is effective in RA treatment. However …

Osteoarthritis (OA), one of the most common joint disease, affects more than 80% of the
population aged 70 or over. Mesenchymal stem cells (MSCs) show multi-potent …