Mesenchymal Stem Cells and Myeloid-Derived Suppressor Cells Interplay in Adjuvant-Induced Arthritis Rat Model

FAM Abo-Aziza, BM Wasfy, SMR Wahba… - International …, 2023 - Elsevier
There has not been much researchs on the biological relationship between myeloid-derived
suppressor cells (MDSCs) and mesenchymal stem cells (MSCs). The goal of the current …

[HTML][HTML] Interaction between mesenchymal stem cells and the immune system in rheumatoid arthritis

D Bačenková, M Trebuňová, R Morochovič, E Dosedla… - Pharmaceuticals, 2022 - mdpi.com
Rheumatoid arthritis (RA) is an autoimmune disease that causes damage to joints. This
review focuses on the possibility of influencing the disease through immunomodulation by …

[HTML][HTML] Genetic mismatch affects the immunosuppressive properties of mesenchymal stem cells in vitro and their ability to influence the course of collagen-induced …

C Sullivan, JM Murphy, MD Griffin, RM Porter… - Arthritis Research & …, 2012 - Springer
Introduction The immunological and homing properties of mesenchymal stem cells (MSCs)
provide a potentially attractive treatment for arthritis. The objective of this study was to …

Interactions of mesenchymal stromal/stem cells and immune cells following MSC-based therapeutic approaches in rheumatoid arthritis

S Dehnavi, M Sadeghi, JT Afshari, M Mohammadi - Cellular Immunology, 2023 - Elsevier
Rheumatoid arthritis (RA) is considered to be a degenerative and progressive autoimmune
disorder. Although several medicinal regimens are used to treat RA, potential adverse …

[HTML][HTML] Mixed cell therapy of bone marrow-derived mesenchymal stem cells and articular cartilage chondrocytes ameliorates osteoarthritis development

I Prasadam, A Akuien, TE Friis, W Fang, X Mao… - Laboratory …, 2018 - nature.com
Of the many cell-based treatments that have been tested in an effort to regenerate
osteoarthritic articular cartilage, none have ever produced cartilage that compare with native …

Treatment of experimental arthritis by inducing immune tolerance with human adipose‐derived mesenchymal stem cells

MA González, E Gonzalez‐Rey, L Rico… - … : Official Journal of …, 2009 - Wiley Online Library
Objective Rheumatoid arthritis (RA) is a chronic autoimmune disease caused by loss of
immunologic self tolerance and characterized by chronic joint inflammation. Adult …

Immunomodulatory effect of mesenchymal stem cells following intra-articular injection in a model of osteoarthritis: a potential role for apoptosis

P Mancuso, MJ Murphy, F Barry - Osteoarthritis and Cartilage, 2017 - oarsijournal.com
Purpose: Mesenchymal stem cells (MSCs) promote regeneration when intra-articularly (IA)
administered in pre-clinical models of osteoarthritis (OA). Their mechanism of action …

[HTML][HTML] Not single but periodic injections of synovial mesenchymal stem cells maintain viable cells in knees and inhibit osteoarthritis progression in rats

N Ozeki, T Muneta, H Koga, Y Nakagawa… - Osteoarthritis and …, 2016 - Elsevier
Objective We investigated the effects of single or repetitive intra-articular injections of
synovial mesenchymal stem cells (MSCs) on a rat osteoarthritis (OA) model, and elucidated …

[PDF][PDF] Anti-inflammatory and antioxidant effects of mesenchymal and hematopoietic stem cells in a rheumatoid arthritis rat model

H Abdelmawgoud, A Saleh - Adv Clin Exp Med, 2018 - dbc.wroc.pl
Abstract Background. Mesenchymal stem cells (MSCs) are of increased importance
because of their capacity to counteract inflammation and suppress host immune responses …

[HTML][HTML] Combination therapy of mesenchymal stromal cells and interleukin-4 attenuates rheumatoid arthritis in a collagen-induced murine model

SM Haikal, NF Abdeltawab, LA Rashed, TI Abd El-Galil… - Cells, 2019 - mdpi.com
Rheumatoid arthritis (RA) is a disease of the joints that causes decreased quality of life.
Mesenchymal stromal cells (MSCs) have immunosuppressive properties, with possible use …