Clinical-grade human embryonic stem cell-derived mesenchymal stromal cells ameliorate the progression of osteoarthritis in a rat model
D Xing, K Wang, J Wu, Y Zhao, W Liu, JJ Li, T Gao… - Molecules, 2021 - mdpi.com
Mesenchymalstem cell (MSC)-based therapy is being increasingly explored in preclinical
and clinical studies as a regenerative method for treating osteoarthritis (OA). However, the …
and clinical studies as a regenerative method for treating osteoarthritis (OA). However, the …
Mesenchymal stromal cells versus betamethasone can dampen disease activity in the collagen arthritis mouse model
ESM El-Denshary, LA Rashed, M Elhussiny - Clinical and experimental …, 2014 - Springer
The objective of this study was to compare between the effects of mesenchymal stem cell
(MSC) and betamethasone in the treatment of rheumatoid arthritis. Sixty male albino mice …
(MSC) and betamethasone in the treatment of rheumatoid arthritis. Sixty male albino mice …
Mesenchymal stem cell therapy in a rat model of osteoarthritis
GM Van Buul, M Siebelt, MJ Leijs, P Bos… - Osteoarthritis and …, 2012 - oarsijournal.com
Purpose: Mesenchymal stem cells (MSCs) are promising candidates for cartilage
regeneration and osteoarthritis (OA) therapies, due to their ability to form cartilage and to …
regeneration and osteoarthritis (OA) therapies, due to their ability to form cartilage and to …
Direct transplantation of mesenchymal stem cells into the knee joints of Hartley strain guinea pigs with spontaneous osteoarthritis
M Sato, K Uchida, H Nakajima, T Miyazaki… - Arthritis research & …, 2012 - Springer
Abstract Introduction Mesenchymal stem cells (MSCs) can differentiate into various
connective tissue cells. Several techniques have been used for the clinical application of …
connective tissue cells. Several techniques have been used for the clinical application of …
[HTML][HTML] Cell source-dependent in vivo immunosuppressive properties of mesenchymal stem cells derived from the bone marrow and synovial fluid of minipigs
WJ Lee, YS Hah, SA Ock, JH Lee, RH Jeon… - Experimental Cell …, 2015 - Elsevier
The in vitro differentiation and immunosuppressive capacity of mesenchymal stem cells
(MSCs) derived from synovial fluid (SF-MSCs) and bone marrow extract (BM-MSCs) in an …
(MSCs) derived from synovial fluid (SF-MSCs) and bone marrow extract (BM-MSCs) in an …
The Therapeutic Potential of Bone Marrow Mesenchymal Stem Cells for Articular Cartilage Regeneration in Osteoarthritis.
N Ding, E Li, X Ouyang, J Guo, B Wei - Current Stem Cell Research …, 2021 - europepmc.org
Osteoarthritis (OA), characterized by the degeneration and destruction of articular cartilage,
is one of the most significant public health issues around the world. In the course of OA …
is one of the most significant public health issues around the world. In the course of OA …
Mesenchymal stem cells: Current concepts in the management of inflammation in osteoarthritis
Osteoarthritis (OA) has traditionally been known as a “wear and tear” disease, which is
mainly characterized by the degradation of articular cartilage and changes in the …
mainly characterized by the degradation of articular cartilage and changes in the …
Mesenchymal stem cells overexpressing interleukin-10 attenuate collagen-induced arthritis in mice
JJ Choi, SA Yoo, SJ Park, YJ Kang… - Clinical & …, 2008 - academic.oup.com
Mesenchymal stem cells (MSCs) have the inherent ability to migrate to multiple organs and
to exert immunosuppressive activity. The aim of this study was to investigate the anti …
to exert immunosuppressive activity. The aim of this study was to investigate the anti …
Human bone marrow mesenchymal Stromal/Stem cells regulate the Proinflammatory response of Monocytes and myeloid dendritic cells from patients with rheumatoid …
P Laranjeira, M Pedrosa, C Duarte, S Pedreiro… - Pharmaceutics, 2022 - mdpi.com
Rheumatoid arthritis (RA) is a disabling autoimmune disease whose treatment is ineffective
for one-third of patients. Thus, the immunomodulatory potential of mesenchymal …
for one-third of patients. Thus, the immunomodulatory potential of mesenchymal …
A1. 10 Human bone marrow-derived mesenchymal stromal cells strongly inhibit cytokine production by naive, memory and effector CD4+ and CD8+ T cells from …
M Pedrosa, C Duarte, P Laranjeira, J Gomes, T Ribeiro… - 2015 - ard.bmj.com
Background and objectives Rheumatoid arthritis (RA) is a chronic inflammatory disease
characterised by autoimmune activation leading to local and systemic consequences. Self …
characterised by autoimmune activation leading to local and systemic consequences. Self …