Mesenchymal stem cell therapy for osteoarthritis: how apoptotic cells modulate inflammation
P Mancuso, AJ Burke, S Raman, AE Ryan… - Osteoarthritis and …, 2018 - oarsijournal.com
Purpose: Mesenchymal stem cells (MSCs) enhance regeneration when locally delivered in
pre-clinical models of osteoarthritis (OA). Their mechanism of action, however, is still poorly …
pre-clinical models of osteoarthritis (OA). Their mechanism of action, however, is still poorly …
Mesenchymal stem cell antigenicity is suppressed in an inflamed joint environment
J Hill, J Cassano, M Goodale… - Osteoarthritis and …, 2017 - oarsijournal.com
Purpose: Osteoarthritis (OA) is one of the leading causes of decreased athletic performance
in people and horses. Treatment with autologous mesenchymal stem cells (MSCs) has been …
in people and horses. Treatment with autologous mesenchymal stem cells (MSCs) has been …
Paradoxical effects of human adipose tissue-derived mesenchymal stem cells on progression of experimental arthritis in SKG mice
JH Kim, YT Lee, K Oh, J Cho, DS Lee, Y Hwang - Cellular immunology, 2014 - Elsevier
We evaluated the therapeutic effect of human adipose tissue-derived mesenchymal stem
cells (hAd-MSCs) in a SKG arthritis model, a relevant animal model for human rheumatoid …
cells (hAd-MSCs) in a SKG arthritis model, a relevant animal model for human rheumatoid …
[HTML][HTML] Effects of mesenchymal stem cells on interleukin-1β-treated chondrocytes and cartilage in a rat osteoarthritic model
J Tang, W Cui, F Song, C Zhai… - Molecular …, 2015 - spandidos-publications.com
In the present study, the effects and mechanisms of mesenchymal stem cells (MSCs) on
interleukin (IL)-1β‑stimulated rat chondrocytes, as well as cartilage from a rat model of …
interleukin (IL)-1β‑stimulated rat chondrocytes, as well as cartilage from a rat model of …
Mesenchymal stem cells in synovial fluid increase in number in response to synovitis and display more tissue-reparative phenotypes in osteoarthritis
Background Synovial fluid mesenchymal stem cells (SF-MSCs) originate in the synovium
and contribute to the endogenous repair of damaged intra-articular tissues. Here, we …
and contribute to the endogenous repair of damaged intra-articular tissues. Here, we …
Mesenchymal stromal cell immunology for efficient and safe treatment of osteoarthritis
M Najar, J Martel-Pelletier, JP Pelletier… - Frontiers in cell and …, 2020 - frontiersin.org
Mesenchymal stem cell (MSC) therapy represents a promising approach for the treatment of
osteoarthritis (OA). MSCs can be readily isolated from multiple sources and expanded ex …
osteoarthritis (OA). MSCs can be readily isolated from multiple sources and expanded ex …
Allogeneic murine mesenchymal stem cells: migration to inflamed joints in vivo and amelioration of collagen induced arthritis when transduced to express CTLA4Ig
Despite the immunosuppressive, homing, and regenerative capabilities of mesenchymal
stem cells (MSCs), their ability to migrate to arthritic joints and influence the course of …
stem cells (MSCs), their ability to migrate to arthritic joints and influence the course of …
[PDF][PDF] Human mesenchymal stem cells as a tool for joint repair in rheumatoid arthritis
Y Tanaka - Clin Exp Rheumatol, 2015 - clinexprheumatol.org
Rheumatoid arthritis (RA) is characterised with chronic inflammatory synovitis and
progressive joint. Because damaged and/or deformed joints cannot be repaired, a novel …
progressive joint. Because damaged and/or deformed joints cannot be repaired, a novel …
Administering human adipose-derived mesenchymal stem cells to prevent and treat experimental arthritis
B Zhou, J Yuan, Y Zhou, M Ghawji Jr, YP Deng… - Clinical …, 2011 - Elsevier
Rheumatoid arthritis is a chronic autoimmune disease and affecting approximately 1% of the
population. Human adipose-derived mesenchymal stem cells (hASCs) were recently found …
population. Human adipose-derived mesenchymal stem cells (hASCs) were recently found …
Therapeutic potential of autologous mesenchymal stem cells derived from synovial fluid in patients with degenerative arthritis
The possibility to isolate synovial fluid-derived mesenchymal stem cells (SFMSCs) from
patients with degenerative arthropathy has been an interest since synovial fluid (SF) from …
patients with degenerative arthropathy has been an interest since synovial fluid (SF) from …