Clinical management of brain tumors and investigations into new therapies requires the
ability to assess repeatedly the response of disease to treatment. Magnetic resonance …

Magnetic resonance imaging is an indispensable tool for both day-to-day management of
brain tumor patients and neuro-oncology clinical trails. While recognizing the value of …

Brain tumors are a heterogeneous group of neoplasm with a diverse histological, molecular,
and genetic spectrum and a widely variable clinical course and prognosis. Although most …

Introduction: The post-treatment monitoring of glioma patients remains an area of active
research and development. Conventional imaging with MRI is a highly sensitive modality for …

Abstract Purpose of Review Neuroimaging plays a critical role in diagnosis of brain tumors
and in assessment of response to therapy. However, challenges remain, including …

FDA approval of oncology therapies requires demonstration of direct clinical benefit
measured by improvement in how patients “function, feel or survive.” 1 Prolonged overall …

Abstract Purpose of Review The neuro-oncology team faces a unique challenge when
assessing treatment response in patients diagnosed with glioblastoma. Magnetic resonance …

Over the past 20 years, very few agents have been approved for the treatment of brain
tumors. Recent studies have highlighted some of the challenges in assessing activity in …

Despite the efforts spent in clinical trials in neuro-oncology during the last few decades,
many challenges remain in the radiologic evaluation of brain tumors and metastases. This …

Magnetic resonance imaging (MRI) provides essential information on anatomical location
and morphology for diagnosis, therapy planning, and treatment evaluation in brain tumors …