Therapeutic approaches to enhance natural killer cell cytotoxicity against cancer: the force awakens
RW Childs, M Carlsten - Nature reviews Drug discovery, 2015 - nature.com
Scientific insights into the human immune system have recently led to unprecedented
breakthroughs in immunotherapy. In the twenty-first century, drugs and cell-based therapies …
breakthroughs in immunotherapy. In the twenty-first century, drugs and cell-based therapies …
Natural killer cell immunotherapy for cancer: a new hope
S Srivastava, A Lundqvist, RW Childs - Cytotherapy, 2008 - Elsevier
Recently there has been a substantial gain in our understanding of the role NK-cells play in
mediating innate host immune responses. Although NK cells have long been known to …
mediating innate host immune responses. Although NK cells have long been known to …
Harnessing natural killer cells for cancer immunotherapy: dispatching the first responders
NA Maskalenko, D Zhigarev… - Nature reviews Drug …, 2022 - nature.com
Natural killer (NK) cells have crucial roles in the innate immunosurveillance of cancer and
viral infections. They are 'first responders' that can spontaneously recognize abnormal cells …
viral infections. They are 'first responders' that can spontaneously recognize abnormal cells …
Prospects for the use of NK cells in immunotherapy of human cancer
HG Ljunggren, KJ Malmberg - Nature Reviews Immunology, 2007 - nature.com
Current insights into the molecular specificities that regulate natural killer (NK)-cell function
suggest that it might be possible to design NK-cell-based immunotherapeutic strategies …
suggest that it might be possible to design NK-cell-based immunotherapeutic strategies …
Natural killer cell‐based immunotherapy in cancer: current insights and future prospects
T Sutlu, E Alici - Journal of internal medicine, 2009 - Wiley Online Library
As our understanding of the molecular mechanisms governing natural killer (NK) cell activity
increases, their potential in cancer immunotherapy is growing increasingly prominent. This …
increases, their potential in cancer immunotherapy is growing increasingly prominent. This …
Advantages and clinical applications of natural killer cells in cancer immunotherapy
The past decade has witnessed a burgeoning of research and further insight into the biology
and clinical applications of natural killer (NK) cells. Once thought to be simple innate cells …
and clinical applications of natural killer (NK) cells. Once thought to be simple innate cells …
Roles of natural killer cells in immunity to cancer, and applications to immunotherapy
NK Wolf, DU Kissiov, DH Raulet - Nature Reviews Immunology, 2023 - nature.com
Great strides have been made in recent years towards understanding the roles of natural
killer (NK) cells in immunity to tumours and viruses. NK cells are cytotoxic innate lymphoid …
killer (NK) cells in immunity to tumours and viruses. NK cells are cytotoxic innate lymphoid …
NK cells for cancer immunotherapy
N Shimasaki, A Jain, D Campana - Nature reviews Drug discovery, 2020 - nature.com
Natural killer (NK) cells can swiftly kill multiple adjacent cells if these show surface markers
associated with oncogenic transformation. This property, which is unique among immune …
associated with oncogenic transformation. This property, which is unique among immune …
Human natural killer cell development and biology
SS Farag, MA Caligiuri - Blood reviews, 2006 - Elsevier
Natural killer cells are important innate immune effector cells with potentially broad
applications in the treatment of human malignancy due to their ability to lyse neoplastic cells …
applications in the treatment of human malignancy due to their ability to lyse neoplastic cells …
The application of natural killer cell immunotherapy for the treatment of cancer
K Rezvani, RH Rouce - Frontiers in immunology, 2015 - frontiersin.org
Natural killer (NK) cells are essential components of the innate immune system and play a
critical role in host immunity against cancer. Recent progress in our understanding of NK cell …
critical role in host immunity against cancer. Recent progress in our understanding of NK cell …