Previous our report indicated that acute application of glial cell line-derived neurotrophic
factor (GDNF) enhances the neuronal excitability of adult rat small-diameter trigeminal …

Glial cell line-derived neurotrophic factor (GDNF) plays an important role in adult sensory
neuron function. However, the acute effects of GDNF on primary sensory neuron excitability …

Neurotrophic factors, such as nerve growth factor and brain-derived neurotrophic factor, are
members of the structurally related neurotrophin family that play important roles in pain …

Glial cell line-derived neurotrophic factor (GDNF) is shown by immunohistochemistry in
human trigeminal sensory system from 22 weeks of gestation to adulthood. In the trigeminal …

Many chronic trigeminal pain conditions, such as migraine or temporo-mandibular disorders,
are associated with inflammation within peripheral endings of trigeminal ganglion (TG) …

Since neuropathic pain is resistant to conventional analgesics such as opiates and non-
steroidal anti-inflammatory drugs, the development of new types of drugs for its treatment …

Glial cell line-derived neurotrophic factor (GDNF), a survival-promoting factor for a subset of
nociceptive small-diameter neurons, has been shown to exert analgesic effects on …

Aims: To identify endogenous sources of glial cell line-derived neurotrophic factor (GDNF) at
the injury site following inferior alveolar nerve transection (IANX) and to determine whether …

To reveal roles of neurotrophic factors in plastic changes of the primary afferent neurons
following nerve injury, we investigated expression of glial cell line-derived neurotrophic …

Background Nerve growth factor (NGF), glial cell line-derived neurotrophic factor (GDNF)
and brain-derived neurotrophic factor (BDNF) all play important roles in the development of …