Cytokine modulation in patients with idiopathic pulmonary fibrosis undergoing treatment with steroids, immunosuppressants, and IFN-γ 1b.

S Marinari, V De Iuliis, V Dadorante… - Journal of Biological …, 2017 - europepmc.org
Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease of unknown etiology and
pathogenic mechanisms. From an etiopathogenic point of view, alveolar macrophages play …

Systemic immune cell activation in a subgroup of patients with idiopathic pulmonary fibrosis

J Homolka, MW Ziegenhagen, KI Gaede, P Entzian… - Respiration, 2003 - karger.com
Background: The prognosis of idiopathic pulmonary fibrosis (IPF/UIP) is poor and its
immunopathogenesis is insufficiently understood. Objectives: The aim of our study was to …

Does interferon‐γ improve pulmonary function in idiopathic pulmonary fibrosis?

A Prasse, KM Müller, C Kurz, H Hamm… - European Respiratory …, 2003 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is a disease with progressive and devastating
deterioration of lung function and a fatal prognosis, despite aggressive therapeutic attempts …

Interferon-γ 1b: impact of new indications (idiopathic pulmonary fibrosis)

AN Aggarwal, D Behera - Expert Opinion on Pharmacotherapy, 2000 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is a relentlessly progressive disease with inadequate
response to conventional treatment with corticosteroids and/or immunosuppressive agents …

The Effect of Inhaled IFN-γ on the Cytokine Profile in the Alveolar Space in Idiopathic Pulmonary Fibrosis (IPF)

S Lau, K Diaz, G Smaldone, R Condos - Chest, 2011 - journal.chestnet.org
PURPOSE: To evaluate how a novel treatment for idiopathic pulmonary fibrosis (IPF)
changes the cytokine profile in the bronchoalveolar lavage (BAL) fluid of IPF patients after …

Idiopathic pulmonary fibrosis: a treatable disease?

U Costabel - European Respiratory Journal, 2003 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease characterised by
fibroblast proliferation and extracellular matrix remodelling. The usual treatment strategy is …

[HTML][HTML] Anti-cytokine therapy in fibrosing alveolitis: where are we now?

A Millar - Respiratory research, 2000 - Springer
Idiopathic pulmonary fibrosis (IPF) is a condition that has a poor prognosis, with a median
survival of 4-5 years irrespective of treatment. Ziesche et al (N Engl J Med 1999, 341: 1264 …

Interferon gamma-1b in the treatment of idiopathic pulmonary fibrosis

MA Pacanowski, GW Amsden - Annals of Pharmacotherapy, 2005 - journals.sagepub.com
Objective: To examine the clinical aspects of idiopathic pulmonary fibrosis (IPF) and the
efficacy and safety of interferon gamma-1b (IFNγ− 1b) in its treatment. Data Sources …

Effects of interferon-γ 1b on biomarker expression in patients with idiopathic pulmonary fibrosis

RM Strieter, KM Starko, RI Enelow, I Noth… - American journal of …, 2004 - atsjournals.org
In a recent study of IFN-γ 1b in 330 patients with idiopathic pulmonary fibrosis (IPF),
progression-free survival was unchanged; however, a trend toward lower mortality was seen …

[HTML][HTML] Cytokine levels in the sera of patients with idiopathic pulmonary fibrosis

PG Tsoutsou, KI Gourgoulianis, E Petinaki… - Respiratory …, 2006 - Elsevier
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a fibroproliferative disorder. Cytokines
contribute an important but yet undefined role to its pathogenesis. OBJECTIVES: The …