Nonsteroidal therapy for idiopathic pulmonary fibrosis

RP Baughman, FO Alabi - Current Opinion in Pulmonary Medicine, 2001 - journals.lww.com
The treatment of interstitial lung disease usually has consisted of corticosteroids with or
without either azathioprine or cyclophosphamide. These drugs mainly target the neutrophil …

The role of chemokines and cytokines in lung fibrosis

MP Keane - European Respiratory Review, 2008 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) exhibits a complex and poorly understood pathogenesis.
Overt inflammation in the lungs of patients with established IPF is absent, and classic anti …

The role of gp130/IL-6 cytokines in the development of pulmonary fibrosis: critical determinants of disease susceptibility and progression?

DA Knight, M Ernst, GP Anderson, YP Moodley… - Pharmacology & …, 2003 - Elsevier
Cryptogenic fibrosing alveolitis (CFA), also known as idiopathic pulmonary fibrosis (IPF), is
the end stage of a heterogeneous group of disorders in which the deposition of excessive …

Antifibrotic therapy for idiopathic pulmonary fibrosis

PS Acharya, DA Zisman - Clinical Pulmonary Medicine, 2001 - journals.lww.com
Idiopathic pulmonary fibrosis (IPF) is a chronic fibrosing interstitial pneumonia characterized
by a poor response to therapy and a dismal prognosis. Historically, the fibrotic process in IPF …

The role of inflammation in the pathogenesis of idiopathic pulmonary fibrosis

BD Bringardner, CP Baran, TD Eubank… - Antioxidants & redox …, 2008 - liebertpub.com
The role of inflammation in idiopathic pulmonary fibrosis (IPF) is controversial. If
inflammation were critical to the disease process, lung pathology would demonstrate an …

Prognostic value of IFN-γ, sCD163, CCL2 and CXCL10 involved in acute exacerbation of idiopathic pulmonary fibrosis

X Gui, X Qiu, Y Tian, M Xie, H Li, Y Gao… - International …, 2019 - Elsevier
Objective Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) is of concern
because of its propensity for rapid deterioration and high mortality. Its aetiology and …

Interferon-γ enhances the antifibrotic effects of pirfenidone by attenuating IPF lung fibroblast activation and differentiation

TN Vu, X Chen, HD Foda, GC Smaldone… - Respiratory …, 2019 - Springer
Background Idiopathic pulmonary fibrosis (IPF) pathogenesis involves multiple pathways,
and combined antifibrotic therapy is needed for future IPF therapy. Inhaled interferon-γ (IFN …

Cytokine phenotypes and the progression of chronic pulmonary fibrosis

SL Kunkel, NW Lukacs, SW Chensue… - Idiopathic Pulmonary …, 2003 - taylorfrancis.com
Fibrosis of the pulmonary interstitium is observed in a wide variety of disorders, including
infectious diseases, autoimmune disorders of connective tissue, and disorders where the …

Interferon gamma-1b as therapy for idiopathic pulmonary fibrosis: an intrapatient analysis

SD Nathan, SD Barnett, B Moran, DL Helman… - Respiration, 2004 - karger.com
Background: The only proven therapeutic option for idiopathic pulmonary fibrosis (IPF) is
lung transplantation. It is biologically plausible that interferon gamma-1b (G-IFN) may halt or …

Interferons and interstitial lung disease

OP Sharma, AG Wilcox - Current opinion in pulmonary medicine, 2000 - journals.lww.com
Downloaded from by BhDMf5ePHKbH4TTImqenVA+ lpWIIBvonhQl60EtgtdlLYrLzSPu+
hQedJnbNaXBf on 11/21/2023 treated with interferon-α for hepatitis C. The patient had …