Therapeutic targets for Alzheimer's disease
A Tarditi, A Caricasole, G Terstappen - Expert Opinion on …, 2009 - Taylor & Francis
Background: Alzheimer's disease (AD), the most common form of degenerative dementia,
represents a tremendous unmet medical need. Although AD had already been described …
represents a tremendous unmet medical need. Although AD had already been described …
Promising heterocycle-based scaffolds in recent (2019–2021) anti-Alzheimer's drug design and discovery
A Dorababu - European Journal of Pharmacology, 2022 - Elsevier
Alzheimer's disease (AD) is one of the neurodegenerative diseases that led to morbidity and
mortality world-wide. It is a complex disease whose etiology is not completely known that …
mortality world-wide. It is a complex disease whose etiology is not completely known that …
Critical evaluation of current Alzheimer's drug discovery (2018–19) & futuristic Alzheimer drug model approach
A Dorababu - Bioorganic Chemistry, 2019 - Elsevier
Abstract Alzheimer′ s disease (AD), a neurodegenerative disease responsible for death of
millions of people worldwide is a progressive clinical disorder which causes neurons to …
millions of people worldwide is a progressive clinical disorder which causes neurons to …
[HTML][HTML] Exploring the therapeutic potential of natural compounds for Alzheimer's disease: mechanisms of action and pharmacological properties
J Liu, T Li, G Zhong, Y Pan, M Gao, S Su… - Biomedicine & …, 2023 - Elsevier
Alzheimer's Disease (AD) is a global public health priority characterized by high mortality
rates in adults and an increasing prevalence in aging populations worldwide. Despite …
rates in adults and an increasing prevalence in aging populations worldwide. Despite …
A critical analysis of new molecular targets and strategies for drug developments in Alzheimer's disease
DK Lahiri, MR Farlow, K Sambamurti… - Current drug …, 2003 - ingentaconnect.com
Alzheimer's disease (AD), a progressive, degenerative disorder of the brain, is believed to
be the most common cause of dementia amongst the elderly. AD is characterized by the …
be the most common cause of dementia amongst the elderly. AD is characterized by the …
Multi-target-directed ligands in Alzheimer's disease treatment
M Bajda, N Guzior, M Ignasik… - Current medicinal …, 2011 - ingentaconnect.com
Among the various drug discovery methods, a very promising modern approach consists in
designing multi-target-directed ligands (MTDLs). This methodology has been specifically …
designing multi-target-directed ligands (MTDLs). This methodology has been specifically …
New trends in the design of drugs against Alzheimer's disease
P Francotte, E Graindorge, S Boverie… - Current medicinal …, 2004 - ingentaconnect.com
First described by Alois Alzheimer in 1907, Alzheimer's disease (AD) is the most common
dementia type, affecting approximately 20 million people worldwide. As the population is …
dementia type, affecting approximately 20 million people worldwide. As the population is …
Current perspectives on pharmacotherapy of Alzheimer's disease
K Chopra, S Misra, A Kuhad - Expert opinion on pharmacotherapy, 2011 - Taylor & Francis
Introduction: Alzheimer's disease (AD) is a daunting public health threat that has prompted
the scientific community's ongoing efforts to decipher the underlying disease mechanism …
the scientific community's ongoing efforts to decipher the underlying disease mechanism …
Drug development for Alzheimer's disease
K Lao, N Ji, X Zhang, W Qiao, Z Tang… - Journal of drug …, 2019 - Taylor & Francis
Alzheimer's disease (AD) is a chronic neurodegenerative disease, which is considered as
one of the most intractable medical problems with heavy social and economic costs. The …
one of the most intractable medical problems with heavy social and economic costs. The …
“It Ain't Over 'til It's Over”aThe Search for Treatments and Cures for Alzheimer's Disease
RJ Hargreaves - ACS Medicinal Chemistry Letters, 2012 - ACS Publications
In the neuroscience landscape, there is no condition with higher unmet medical and societal
need than Alzheimer's disease (AD). There are significant opportunities to improve upon …
need than Alzheimer's disease (AD). There are significant opportunities to improve upon …