Accurate staging of non–small-cell lung cancer (NSCLC) determines prognosis and
facilitates decisions regarding treatment options. Unfortunately, even after an apparently …

Lymph node micrometastases could be one of the reasons for the high recurrence rate after
complete surgical resection in stage I–IIIA non‐small cell lung cancer (NSCLC). The …

Introduction In early stage non-small cell lung cancer (NSCLC), presence of lymphatic
micrometastases and isolated tumor cells, primarily detected by immunohistochemistry, is …

Purpose The survival of patients with non–small-cell lung cancer (NSCLC), even when
resectable, remains poor. Several small studies suggest that occult metastases (OMs) in …

Early metastasis is a well-known feature of poor prognosis in potentially resectable non-
small cell lung cancer (NSCLC). However, a significant number of lymph node-negative …

The ability to detect occult regional and systemic metastases in patients with operable lung
carcinoma could have a significant impact on the management of the disease. Here, we …

Lung cancer has some of the highest morbidity and mortality rates of all cancers, and an
important risk factor for mortality in patients with lung cancer is tumor metastasis. Even if a …

PURPOSE: This study was designed to substantiate the prognostic impact of occult
micrometastatic tumor cells in the lymph nodes (LNs) and bone marrow (BM) in stage I non …

Objective To detect occult micrometastatic tumor cells in pN0 lymph nodes of nonsmall cell
lung cancer (NSCLC) by a combination of cytokeratin and p53 immunohistochemistry …

PURPOSE This prospective study was designed to evaluate the prognostic relevance and
biologic characteristics of a minimal lymphatic tumor load in non-small-cell lung cancer …