[HTML][HTML] In silico analysis and identification of antiviral coumarin derivatives against 3-chymotrypsin-like main protease of the novel coronavirus SARS-CoV-2
Abstract Coronavirus disease 2019 (COVID-19) is a pandemic viral disease caused by
SARS-CoV-2 that generated serious damages for both the human population and the global …
SARS-CoV-2 that generated serious damages for both the human population and the global …
[HTML][HTML] Computational screening for potential drug candidates against the SARS-CoV-2 main protease
Background: SARS-CoV-2 is the causal agent of the current coronavirus disease 2019
(COVID-19) pandemic. They are enveloped, positive-sense, single-stranded RNA viruses of …
(COVID-19) pandemic. They are enveloped, positive-sense, single-stranded RNA viruses of …
Theoretical insights into the anti-SARS-CoV-2 activity of chloroquine and its analogs and in silico screening of main protease inhibitors
AS Achutha, VL Pushpa, S Suchitra - Journal of proteome …, 2020 - ACS Publications
Corona virus disease (COVID-19) is a dangerous disease rapidly spreading all over the
world today. Currently there are no treatment options for it. Drug repurposing studies …
world today. Currently there are no treatment options for it. Drug repurposing studies …
Molecular docking and virtual screening based prediction of drugs for COVID-19
S Talluri - Combinatorial Chemistry & High Throughput …, 2021 - ingentaconnect.com
Aims: To predict potential drugs for COVID-19 by using molecular docking for virtual
screening of drugs approved for other clinical applications. Background: SARS-CoV-2 is the …
screening of drugs approved for other clinical applications. Background: SARS-CoV-2 is the …
In silico screening of phytopolyphenolics for the identification of bioactive compounds as novel protease inhibitors effective against SARS-CoV-2
M Rudrapal, AR Issahaku, C Agoni… - Journal of …, 2022 - Taylor & Francis
Due to the unavailability specific drugs or vaccines (FDA approved) that can cure COVID-19,
the development of potent antiviral drug candidates/therapeutic molecules against COVID …
the development of potent antiviral drug candidates/therapeutic molecules against COVID …
Screening for inhibitors of main protease in SARS-CoV-2: in silico and in vitro approach avoiding peptidyl secondary amides
KZ Yamamoto, N Yasuo, M Sekijima - Journal of Chemical …, 2022 - ACS Publications
In addition to vaccines, antiviral drugs are essential for suppressing COVID-19. Although
several inhibitor candidates were reported for SARS-CoV-2 main protease, most are highly …
several inhibitor candidates were reported for SARS-CoV-2 main protease, most are highly …
Potential of Plant Bioactive Compounds as SARS‐CoV‐2 Main Protease (Mpro) and Spike (S) Glycoprotein Inhibitors: A Molecular Docking Study
Since the outbreak of the COVID‐19 (coronavirus disease 19) pandemic, researchers have
been trying to investigate several active compounds found in plants that have the potential to …
been trying to investigate several active compounds found in plants that have the potential to …
Virtual screening, ADMET prediction and dynamics simulation of potential compounds targeting the main protease of SARS-CoV-2
The coronavirus disease-2019 caused by a novel SARS CoV-2 virus has emerged as a
global threat. Still, no drugs are available for its treatment. The main protease is the most …
global threat. Still, no drugs are available for its treatment. The main protease is the most …
ADMET profile and virtual screening of plant and microbial natural metabolites as SARS-CoV-2 S1 glycoprotein receptor binding domain and main protease inhibitors
In an attempt to search for selective inhibitors against the SARS-CoV-2 which caused
devastating of lives and livelihoods across the globe, 415 natural metabolites isolated from …
devastating of lives and livelihoods across the globe, 415 natural metabolites isolated from …
[HTML][HTML] Binding of inhibitors to the monomeric and dimeric SARS-CoV-2 Mpro
SARS-CoV-2 rapidly infects millions of people worldwide since December 2019. There is
still no effective treatment for the virus, resulting in the death of more than one million …
still no effective treatment for the virus, resulting in the death of more than one million …