Obesity and diabetes: the increased risk of cancer and cancer-related mortality

EJ Gallagher, D LeRoith - Physiological reviews, 2015 - journals.physiology.org
Obesity and type 2 diabetes are becoming increasingly prevalent worldwide, and both are
associated with an increased incidence and mortality from many cancers. The metabolic …

Obesity, type-2 diabetes and cancer: mechanistic insights

K Kashfi, CL Rosen, M Aslan - Critical Reviews™ in …, 2019 - dl.begellhouse.com
Obesity leads to many diseases including hypercholesterolemia, type-2 diabetes,
hypertension, cardiovascular disease, and cancer. It is the fastest-growing lethal disease in …

[HTML][HTML] Obesity, type 2 diabetes, and cancer risk

T Scully, A Ettela, D LeRoith, EJ Gallagher - Frontiers in oncology, 2021 - frontiersin.org
Obesity and type 2 diabetes have both been associated with increased cancer risk and are
becoming increasingly prevalent. Metabolic abnormalities such as insulin resistance and …

Obesity and cancer pathogenesis

NA Berger - Annals of the New York Academy of Sciences, 2014 - Wiley Online Library
Overweight and obesity have reached pandemic levels on a worldwide basis and are
associated with increased risk and worse prognosis for many but not all malignancies …

Cancer, obesity, diabetes, and antidiabetic drugs: is the fog clearing?

AJ Klil-Drori, L Azoulay, MN Pollak - Nature reviews Clinical oncology, 2017 - nature.com
The prevalence of obesity, of type 2 diabetes mellitus (T2DM), and of cancer are all
increasing globally. The relationships between these diseases are complex, and thus …

Diabetes and cancer: two diseases with obesity as a common risk factor

SK Garg, H Maurer, K Reed… - Diabetes, Obesity and …, 2014 - Wiley Online Library
There is a growing body of evidence to support a connection between diabetes
(predominantly type 2), obesity and cancer. Multiple meta‐analyses of epidemiological data …

New horizons: epidemiology of obesity, diabetes mellitus, and cancer prognosis

S Harborg, KA Kjærgaard, RW Thomsen… - The Journal of …, 2024 - academic.oup.com
The global prevalence of obesity and diabetes mellitus has increased in parallel with
increasing cancer incidence, due to environmental and lifestyle factors and population …

[HTML][HTML] Epidemiology and molecular mechanisms tying obesity, diabetes, and the metabolic syndrome with cancer

EJ Gallagher, D LeRoith - Diabetes care, 2013 - ncbi.nlm.nih.gov
It is well recognized that the world is witnessing an epidemic of obesity and type 2 diabetes
(T2D). Numerous studies have shown that both obesity and T2D are associated with an …

Diabetes, obesity, and cancer—pathophysiology and clinical implications

IC Lega, LL Lipscombe - Endocrine reviews, 2020 - academic.oup.com
Obesity and diabetes have both been associated with an increased risk of cancer. In the
face of increasing obesity and diabetes rates worldwide, this is a worrying trend for cancer …

[HTML][HTML] Epidemiological link between obesity, type 2 diabetes mellitus and cancer

CJ Fernandez, AS George… - World Journal of …, 2021 - ncbi.nlm.nih.gov
There exists a complex interaction between obesity, type 2 diabetes mellitus (T2DM) and
cancer, and an increase in the incidence of cancer is expected with the growing obesity …