[HTML][HTML] Synthesis, biological and medicinal impacts of metallodrugs: A study
The behavior of metals and metallodrugs in biological systems affects the setup of
therapeutic strategies with a distinct mode of action and new knowledge of clinically-proven …
therapeutic strategies with a distinct mode of action and new knowledge of clinically-proven …
Medicinal inorganic chemistry: An updated review on the status of metallodrugs and prominent metallodrug candidates
VM Miranda - Reviews in Inorganic Chemistry, 2022 - degruyter.com
Metallodrugs correspond to a small portion of all available drugs in the market and, yet,
some of them are among the most used and important drugs in modern medicine. However …
some of them are among the most used and important drugs in modern medicine. However …
Application of metallomics and metalloproteomics for understanding the molecular mechanisms of action of metal-based drugs
Metals play a significant role in biological processes, and metal-based drugs nowadays
have been commonly used for therapeutic and diagnostic purposes. However, due to severe …
have been commonly used for therapeutic and diagnostic purposes. However, due to severe …
Coordination and bioinorganic chemistry at the heart of metallodrugs: Knowledge gaps and future directions
Transition metals are an integral part of medicinal inorganic chemistry. These metals exist in
distinct oxidation states and are found to interact with several negatively charged molecules …
distinct oxidation states and are found to interact with several negatively charged molecules …
[PDF][PDF] The importance of metal-based drugs in medicinal inorganic chemistry to improve life quality of patients
M Varol - Journal of applied pharmacy, 2016 - researchgate.net
Most of metal ions are essential components to maintain human homeostasis and play
crucial roles in many biological processes by involving as cofactors in the biological function …
crucial roles in many biological processes by involving as cofactors in the biological function …
[HTML][HTML] From the Discovery of Targets to Delivery Systems: How to Decipher and Improve the Metallodrugs' Actions at a Molecular Level
I Iacobucci, S La Manna, I Cipollone, V Monaco… - Pharmaceutics, 2023 - mdpi.com
Metals are indispensable for the life of all organisms, and their dysregulation leads to
various disorders due to the disruption of their homeostasis. Nowadays, various transition …
various disorders due to the disruption of their homeostasis. Nowadays, various transition …
Advancement of metal compounds as therapeutic and diagnostic metallodrugs: Current frontiers and future perspectives
Coordination compounds on account of distinctive features of metal ions that include
variable oxidation states, diverse range of geometries and coordination numbers …
variable oxidation states, diverse range of geometries and coordination numbers …
[PDF][PDF] Transition metal complexes as potential therapeutic agents
Transition metals have an important place within medicinal biochemistry. Research has
shown significant progress in utilization of transition metal complexes as drugs to treat …
shown significant progress in utilization of transition metal complexes as drugs to treat …
Metal complexes in medicine an overview and update from drug design perspective
RK Sodhi, S Paul - Cancer Therapy & Oncology International …, 2019 - ideas.repec.org
Metals are essential cellular components selected by nature to function in several
indispensable biochemical processes for living organisms. Transition metal complexes are …
indispensable biochemical processes for living organisms. Transition metal complexes are …
Metallodrugs in cancer therapy: past, present and new strategies
I Kostova - Frontiers in Chemistry, 2024 - frontiersin.org
Cancer diagnostics and therapy that include metal-based pharmaceuticals have improved
over the past decades. The therapeutic importance and application of metals and their …
over the past decades. The therapeutic importance and application of metals and their …