[HTML][HTML] Synthesis, biological and medicinal impacts of metallodrugs: A study

E Kabir, MROK Noyon, MA Hossain - Results in Chemistry, 2023 - Elsevier
The behavior of metals and metallodrugs in biological systems affects the setup of
therapeutic strategies with a distinct mode of action and new knowledge of clinically-proven …

Medicinal inorganic chemistry: An updated review on the status of metallodrugs and prominent metallodrug candidates

VM Miranda - Reviews in Inorganic Chemistry, 2022 - degruyter.com
Metallodrugs correspond to a small portion of all available drugs in the market and, yet,
some of them are among the most used and important drugs in modern medicine. However …

Application of metallomics and metalloproteomics for understanding the molecular mechanisms of action of metal-based drugs

Y Wang, H Wang, H Li, H Sun - Essential and Non-essential Metals …, 2017 - Springer
Metals play a significant role in biological processes, and metal-based drugs nowadays
have been commonly used for therapeutic and diagnostic purposes. However, due to severe …

Coordination and bioinorganic chemistry at the heart of metallodrugs: Knowledge gaps and future directions

NB Sadeer, R Varghese, S Ramamoorthy… - Inorganica Chimica …, 2024 - Elsevier
Transition metals are an integral part of medicinal inorganic chemistry. These metals exist in
distinct oxidation states and are found to interact with several negatively charged molecules …

[PDF][PDF] The importance of metal-based drugs in medicinal inorganic chemistry to improve life quality of patients

M Varol - Journal of applied pharmacy, 2016 - researchgate.net
Most of metal ions are essential components to maintain human homeostasis and play
crucial roles in many biological processes by involving as cofactors in the biological function …

[HTML][HTML] From the Discovery of Targets to Delivery Systems: How to Decipher and Improve the Metallodrugs' Actions at a Molecular Level

I Iacobucci, S La Manna, I Cipollone, V Monaco… - Pharmaceutics, 2023 - mdpi.com
Metals are indispensable for the life of all organisms, and their dysregulation leads to
various disorders due to the disruption of their homeostasis. Nowadays, various transition …

Advancement of metal compounds as therapeutic and diagnostic metallodrugs: Current frontiers and future perspectives

I Yousuf, M Bashir, F Arjmand, S Tabassum - Coordination Chemistry …, 2021 - Elsevier
Coordination compounds on account of distinctive features of metal ions that include
variable oxidation states, diverse range of geometries and coordination numbers …

[PDF][PDF] Transition metal complexes as potential therapeutic agents

S Rafique, M Idrees, A Nasim… - Biotechnology and …, 2010 - academicjournals.org
Transition metals have an important place within medicinal biochemistry. Research has
shown significant progress in utilization of transition metal complexes as drugs to treat …

Metal complexes in medicine an overview and update from drug design perspective

RK Sodhi, S Paul - Cancer Therapy & Oncology International …, 2019 - ideas.repec.org
Metals are essential cellular components selected by nature to function in several
indispensable biochemical processes for living organisms. Transition metal complexes are …

Metallodrugs in cancer therapy: past, present and new strategies

I Kostova - Frontiers in Chemistry, 2024 - frontiersin.org
Cancer diagnostics and therapy that include metal-based pharmaceuticals have improved
over the past decades. The therapeutic importance and application of metals and their …