Compounds isolated from Magnolia officinalis such as magnolol, honokiol and obovatol
exhibit several pharmacological effects on CNS including depressant, anxiolytic and …

Previously, we found that obovatol, a lignan compound isolated from Magnolia officinalis,
has anti-cancer, anti-inflammatory, and anxiolytic effects. Recent studies showed that …

Honokiol, a main biphenyl neolignan of the traditional crude medicine, Magnoliae cortex,
was found to show neurotrophic activity on the cultures of rat cortical neurons at …

We have found that honokiol [4-allyl-2-(3-allyl-4-hydroxy-phenyl)-phenol] can promote
neurite outgrowth and mobilize intracellular Ca2+ store in primary cultured rat cortical …

The neurite outgrowth-promoting effects of scoparone isolated from the stem bark of
Liriodendron tulipifera were investigated in PC12 cells. At a concentration of 200μM …

Background Honokiol, an active component isolated and purified from Chinese traditional
herb Magnolia officinalis. It is known to have a wide range of biological activities including …

Nerve growth factor (NGF) promotes axonal growth in PC12 cells primarily by regulating the
RTK-RAS-MEK-ERK pathway. Panaxydol, a polyacetylene isolated from Panax …

Depression is a common psychiatric disorder that affects almost 10% of children and
adolescents worldwide. Numerous synthetic chemical antidepressants used to treat …

Abstract NS-417 (5-(4-Chlorophenyl)-8-methyl-6-7-8-9-tetrahydro-1-H-pyrrolo [3.2-h]
isoquinoline-2, 3-dione-3-oxim hydrochloric acid salt) belongs to a new chemical series of …

Donepezil is a potent and selective acetylcholinesterase inhibitor developed for the
treatment of Alzheimer's disease. To elucidate whether donepezil causes neuronal …