[HTML][HTML] Senile osteoporosis: the involvement of differentiation and senescence of bone marrow stromal cells
A Qadir, S Liang, Z Wu, Z Chen, L Hu… - International journal of …, 2020 - mdpi.com
Senile osteoporosis has become a worldwide bone disease with the aging of the world
population. It increases the risk of bone fracture and seriously affects human health. Unlike …
population. It increases the risk of bone fracture and seriously affects human health. Unlike …
[HTML][HTML] Osteogenesis and aging: lessons from mesenchymal stem cells
A Infante, CI Rodríguez - Stem cell research & therapy, 2018 - Springer
Aging is a high risk factor for the development of osteoporosis, a multifactorial age-related
progressive disease characterized by reduced bone mass and increased risk of fractures. At …
progressive disease characterized by reduced bone mass and increased risk of fractures. At …
[HTML][HTML] Mesenchymal progenitors in osteopenias of diverse pathologies: differential characteristics in the common shift from osteoblastogenesis to adipogenesis
Osteoporosis is caused by pathologic factors such as aging, hormone deficiency or excess,
inflammation and systemic diseases like diabetes. Bone marrow stromal cells (BMSCs), the …
inflammation and systemic diseases like diabetes. Bone marrow stromal cells (BMSCs), the …
[HTML][HTML] Mesenchymal stem cells: cell fate decision to osteoblast or adipocyte and application in osteoporosis treatment
L Hu, C Yin, F Zhao, A Ali, J Ma, A Qian - International Journal of …, 2018 - mdpi.com
Osteoporosis is a progressive skeletal disease characterized by decreased bone mass and
degraded bone microstructure, which leads to increased bone fragility and risks of bone …
degraded bone microstructure, which leads to increased bone fragility and risks of bone …
[HTML][HTML] Differentiation of bone marrow mesenchymal stem cells in osteoblasts and adipocytes and its role in treatment of osteoporosis
C Wang, H Meng, X Wang, C Zhao… - … medical journal of …, 2016 - ncbi.nlm.nih.gov
Osteoporosis is a systemic metabolic bone disorder characterized by a decrease in bone
mass and degradation of the bone microstructure, leaving bones that are fragile and prone …
mass and degradation of the bone microstructure, leaving bones that are fragile and prone …
[HTML][HTML] Insulin impedes osteogenesis of BMSCs by inhibiting autophagy and promoting premature senescence via the TGF-β1 pathway
P Zhang, H Zhang, J Lin, T Xiao, R Xu, Y Fu… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
The dysfunction of bone marrow stromal cells (BMSCs) may be a core factor in Type 2
diabetes mellitus (T2DM) associated osteoporosis. However, the underlying mechanism is …
diabetes mellitus (T2DM) associated osteoporosis. However, the underlying mechanism is …
Aging and lineage allocation changes of bone marrow skeletal (stromal) stem cells
JO Nehlin, A Jafari, M Tencerova, M Kassem - Bone, 2019 - Elsevier
Aging is associated with decreased bone mass and accumulation of bone marrow
adipocytes. Both bone forming osteoblastic cells and bone marrow adipocytes are derived …
adipocytes. Both bone forming osteoblastic cells and bone marrow adipocytes are derived …
[HTML][HTML] In osteoporosis, differentiation of mesenchymal stem cells (MSCs) improves bone marrow adipogenesis
AM Pino, CJ Rosen, JP Rodríguez - Biological research, 2012 - SciELO Chile
The formation, maintenance, and repair of bone tissue involve close interlinks between two
stem cell types housed in the bone marrow: the hematologic stem cell originating …
stem cell types housed in the bone marrow: the hematologic stem cell originating …
[HTML][HTML] Skeletal aging and osteoporosis: mechanisms and therapeutics
A Chandra, J Rajawat - International journal of molecular sciences, 2021 - mdpi.com
Bone is a dynamic organ maintained by tightly regulated mechanisms. With old age, bone
homeostasis, which is maintained by an intricate balance between bone formation and bone …
homeostasis, which is maintained by an intricate balance between bone formation and bone …
Prospect of mesenchymal stem cells in therapy of osteoporosis: a review
Osteoporosis is a systemic skeletal disease associated with reduced bone strong point that
results in raised fracture risk, with decreased bone strength, leading to reduced bone …
results in raised fracture risk, with decreased bone strength, leading to reduced bone …