Honokiol analogs: a novel class of anticancer agents targeting cell signaling pathways and other bioactivities

A Kumar, U Kumar Singh… - Future Medicinal …, 2013 - Taylor & Francis
Honokiol (3, 5-di-(2-propenyl)-1, 1-biphenyl-2, 2-diol) is a natural bioactive neolignan
isolated from the genus Magnolia. In recent studies, honokiol has been observed to have …

Honokiol: a novel natural agent for cancer prevention and therapy

S Arora, S Singh, GA Piazza… - Current molecular …, 2012 - ingentaconnect.com
Honokiol (3', 5-di-(2-propenyl)-1, 1'-biphenyl-2, 4'-diol) is a bioactive natural product derived
from Magnolia spp. Recent studies have demonstrated anti-inflammatory, anti-angiogenic …

[HTML][HTML] Honokiol: a review of its anticancer potential and mechanisms

CP Ong, WL Lee, YQ Tang, WH Yap - Cancers, 2019 - mdpi.com
Cancer is characterised by uncontrolled cell division and abnormal cell growth, which is
largely caused by a variety of gene mutations. There are continuous efforts being made to …

Molecular targets of Honokiol: a promising phytochemical for effective cancer management

C Averett, S Arora, H Zubair, S Singh, A Bhardwaj… - The Enzymes, 2014 - Elsevier
Honokiol is a bioactive, biphenolic phytochemical, present in the aerial parts of plants
classified under the genus Magnolia. It has been an important constituent of Asian traditional …

Honokiol and its analogues as anticancer compounds: Current mechanistic insights and structure-activity relationship

P Prasher, R Fatima, M Sharma, B Tynybekov… - Chemico-biological …, 2023 - Elsevier
Lignans are plant-derived polyphenolic compounds with a plethora of biological
applications. Also, regarded as phytoestrogens, the lignans offer a variety of health benefits …

Honokiol, a multifunctional antiangiogenic and antitumor agent

LE Fried, JL Arbiser - Antioxidants & redox signaling, 2009 - liebertpub.com
Honokiol is a small-molecule polyphenol isolated from the genus Magnolia. It is
accompanied by other related polyphenols, including magnolol, with which it shares certain …

Honokiol for cancer therapeutics: A traditional medicine that can modulate multiple oncogenic targets

K Banik, AM Ranaware, V Deshpande… - Pharmacological …, 2019 - Elsevier
In spite of billions of dollars expended on cancer research every year, the incidence rate and
the mortality rate due to this widespread disease has increased drastically over the last few …

Honokiol: A review of its pharmacological potential and therapeutic insights

A Rauf, A Olatunde, M Imran, FA Alhumaydhi… - Phytomedicine, 2021 - Elsevier
Background Honokiol is a pleiotropic compound which been isolated from Magnolia species
such as Magnolia grandiflora and Magnolia dealbata. Magnolia species Magnolia …

Synthesis and in vitro antitumor evaluation of honokiol derivatives

M Zhu, B Li, H Ma, X Huang, H Wang, Y Dai, Y Li… - Bioorganic & medicinal …, 2020 - Elsevier
Honokiol is a natural bioactive neolignan and has been widely researched and structural
modified as an anticancer agent. In this paper, 18 honokiol derivatives were synthesized …

Honokiol, an Active Compound of Magnolia Plant, Inhibits Growth, and Progression of Cancers of Different Organs

R Prasad, SK Katiyar - Anti-inflammatory Nutraceuticals and Chronic …, 2016 - Springer
Abstract Honokiol (C 18 H 18 O 2) is a biphenolic natural product isolated from the bark and
leaves of Magnolia plant spp. During the last decade or more, honokiol has been …