Background Many physiological and/or pathological conditions lead to muscle
deconditioning, a well‐described phenomenon characterized by a loss of strength and …

From the perspective of a muscle physiologist, adipose tissue has long been perceived
predominantly as a fuel reservoir that provides muscle and other tissues with NEFA when …

Background Association between inflammatory markers and intermuscular adipose tissue
(IMAT) has been reported. We hypothesized that subclinical inflammation of adipose tissue …

OBJECTIVE Adipocyte infiltration of the musculoskeletal system is well recognized as a
hallmark of aging, obesity, and type 2 diabetes. Intermuscular adipocytes might serve as a …

Skeletal muscle is the largest tissue responsible for the insulin-stimulated disposal of
glucose. However, identifying the link between excess body fat and impaired insulin …

Type 2 diabetes is characterized by excessive lipid storage in skeletal muscle. Excessive
intramyocellular lipid (IMCL) storage exceeds intracellular needs and induces lipotoxic …

Insulin resistance has been associated with the accumulation of fat within skeletal muscle
fibers as intramyocellular lipid (IMCL). Here, we have examined in a cross‐sectional study …

OBJECTIVE: Aging is associated with a redistribution of body fat including a relative loss of
subcutaneous peripheral fat. These changes in body fat can have important clinical …

Abstract Perilipin 1 (PLIN1) protein, also known as lipid droplet-associated protein, is
encoded by the PLIN1 gene and is able to anchor itself to the membranes of lipid droplets …

Intramyocellular lipids (IMCL) are stored as discrete lipid droplets which are associated with
a number of proteins. The lipid droplet-associated protein adipophilin (the human …