Short‐term disuse promotes fatty acid infiltration into skeletal muscle
Background Many physiological and/or pathological conditions lead to muscle
deconditioning, a well‐described phenomenon characterized by a loss of strength and …
deconditioning, a well‐described phenomenon characterized by a loss of strength and …
Metabolic and hormonal interactions between muscle and adipose tissue
From the perspective of a muscle physiologist, adipose tissue has long been perceived
predominantly as a fuel reservoir that provides muscle and other tissues with NEFA when …
predominantly as a fuel reservoir that provides muscle and other tissues with NEFA when …
Adipose tissue infiltration in skeletal muscle of healthy elderly men: relationships with body composition, insulin resistance, and inflammation at the systemic and …
E Zoico, A Rossi, V Di Francesco, A Sepe… - … Series A: Biomedical …, 2010 - academic.oup.com
Background Association between inflammatory markers and intermuscular adipose tissue
(IMAT) has been reported. We hypothesized that subclinical inflammation of adipose tissue …
(IMAT) has been reported. We hypothesized that subclinical inflammation of adipose tissue …
Metabolic remodeling of human skeletal myocytes by cocultured adipocytes depends on the lipolytic state of the system
JP Kovalik, D Slentz, RD Stevens, WE Kraus… - Diabetes, 2011 - Am Diabetes Assoc
OBJECTIVE Adipocyte infiltration of the musculoskeletal system is well recognized as a
hallmark of aging, obesity, and type 2 diabetes. Intermuscular adipocytes might serve as a …
hallmark of aging, obesity, and type 2 diabetes. Intermuscular adipocytes might serve as a …
Adipokines as regulators of muscle metabolism and insulin sensitivity
DJ Dyck - Applied Physiology, Nutrition, and Metabolism, 2009 - cdnsciencepub.com
Skeletal muscle is the largest tissue responsible for the insulin-stimulated disposal of
glucose. However, identifying the link between excess body fat and impaired insulin …
glucose. However, identifying the link between excess body fat and impaired insulin …
Perilipin 2 improves insulin sensitivity in skeletal muscle despite elevated intramuscular lipid levels
Type 2 diabetes is characterized by excessive lipid storage in skeletal muscle. Excessive
intramyocellular lipid (IMCL) storage exceeds intracellular needs and induces lipotoxic …
intramyocellular lipid (IMCL) storage exceeds intracellular needs and induces lipotoxic …
Intramyocellular lipid and insulin resistance: differential relationships in European and African Americans
KH Ingram, C Lara‐Castro, BA Gower, R Makowsky… - …, 2011 - Wiley Online Library
Insulin resistance has been associated with the accumulation of fat within skeletal muscle
fibers as intramyocellular lipid (IMCL). Here, we have examined in a cross‐sectional study …
fibers as intramyocellular lipid (IMCL). Here, we have examined in a cross‐sectional study …
Peripheral fat loss and decline in adipogenesis in older humans
G Caso, MA McNurlan, I Mileva, A Zemlyak… - Metabolism, 2013 - Elsevier
OBJECTIVE: Aging is associated with a redistribution of body fat including a relative loss of
subcutaneous peripheral fat. These changes in body fat can have important clinical …
subcutaneous peripheral fat. These changes in body fat can have important clinical …
[HTML][HTML] Function and characterization of the promoter region of perilipin 1 (PLIN1): Roles of E2F1, PLAG1, C/EBPβ, and SMAD3 in bovine adipocytes
Abstract Perilipin 1 (PLIN1) protein, also known as lipid droplet-associated protein, is
encoded by the PLIN1 gene and is able to anchor itself to the membranes of lipid droplets …
encoded by the PLIN1 gene and is able to anchor itself to the membranes of lipid droplets …
Adipophilin distribution and colocalisation with lipid droplets in skeletal muscle
CS Shaw, M Sherlock, PM Stewart… - Histochemistry and cell …, 2009 - Springer
Intramyocellular lipids (IMCL) are stored as discrete lipid droplets which are associated with
a number of proteins. The lipid droplet-associated protein adipophilin (the human …
a number of proteins. The lipid droplet-associated protein adipophilin (the human …