Perilipin2 plays a positive role in adipocytes during lipolysis by escaping proteasomal degradation

Y Takahashi, A Shinoda, H Kamada, M Shimizu… - Scientific reports, 2016 - nature.com
Abstract Perilipin2 (Plin2), also known as adipose differentiation-related protein (ADRP), or
adipophilin, is a member of the PAT family involved in lipid droplet (LD) formation in the liver …

Intramyocellular lipids and insulin resistance

J Machann, H Häring, F Schick… - Diabetes, Obesity and …, 2004 - Wiley Online Library
Lipids are stored not only in adipocytes but also 'ectopically'in tissues such as muscle, liver,
beta cells and others. From a metabolic perspective, intramyocellular lipids (IMCLs) have …

Longitudinal muscle gene expression patterns associated with differential intramuscular fat in cattle

NJ Hudson, A Reverter, PL Greenwood, B Guo… - Animal, 2015 - cambridge.org
Intramuscular fat (IMF) can improve meat product quality through its impact on flavour and
juiciness. High marbling cuts can command premium prices in some countries and grading …

[HTML][HTML] Intramuscular adipose is derived from a non-Pax3 lineage and required for efficient regeneration of skeletal muscles

W Liu, Y Liu, X Lai, S Kuang - Developmental biology, 2012 - Elsevier
Ectopic accumulation of adipose in the skeletal muscle is associated with muscle wasting,
insulin resistance and diabetes. However, the developmental origin of postnatal …

Intramuscular fat and associations with metabolic risk factors in the Framingham Heart Study

KE Therkelsen, A Pedley, EK Speliotes… - … , and vascular biology, 2013 - Am Heart Assoc
Objective—Intramuscular fat accumulates between muscle fibers or within muscle cells. We
investigated the association of intramuscular fat with other ectopic fat deposits and metabolic …

Perilipin 5–Driven Lipid Droplet Accumulation in Skeletal Muscle Stimulates the Expression of Fibroblast Growth Factor 21

LALS Harris, JR Skinner, TM Shew, TA Pietka… - Diabetes, 2015 - Am Diabetes Assoc
Perilipin 5 (PLIN5) is a lipid droplet protein and is highly expressed in oxidative tissue.
Expression of the PLIN5 gene is regulated by peroxisome proliferator–activated receptor-α …

Fatty acids regulate perilipin5 in muscle by activating PPARδ [S]

C Bindesb, O Berg, B Arntsen, HI Nebb, KT Dalen - Journal of lipid …, 2013 - ASBMB
The surface of lipid droplets (LDs) in various cell types is coated with perilipin proteins
encoded by the Plin genes. Perilipins regulate LD metabolism by selectively recruiting …

Preadipocyte and adipose tissue differentiation in meat animals: influence of species and anatomical location

GJ Hausman, U Basu, S Wei… - Annu. Rev. Anim …, 2014 - annualreviews.org
Early in porcine adipose tissue development, the stromal-vascular (SV) elements control
and dictate the extent of adipogenesis in a depot-dependent manner. The vasculature and …

Enhancing intramuscular fat development via targeting fibro-adipogenic progenitor cells in meat animals

X Li, X Fu, G Yang, M Du - Animal, 2020 - cambridge.org
In the livestock industry, subcutaneous and visceral fat pads are considered as wastes,
while intramuscular fat or marbling fat is essential for improving flavor and palatability of …

Decrease in intramuscular lipid droplets and translocation of HSL in response to muscle contraction and epinephrine

C Prats, M Donsmark, K Qvortrup, C Londos… - Journal of lipid …, 2006 - ASBMB
A better understanding of skeletal muscle lipid metabolism is needed to identify the
molecular mechanisms relating intramuscular triglyceride (IMTG) to muscle metabolism and …