Inflammation is a protective response to injury, but it can become chronic, leading to tissue
damage and disease. Cigarette smoke causes multiple inflammatory diseases, which …

Introduction Cigarette smoke is a profound pro-inflammatory stimulus that contributes to
acute lung injuries and to chronic lung disease including COPD (emphysema and chronic …

Chronic obstructive pulmonary disease is characterized, in part, by chronic inflammation that
persists even after smoking cessation, suggesting that a failure to resolve inflammation plays …

Inappropriate or excessive pulmonary inflammation can contribute to chronic lung diseases.
In health, the resolution of inflammation is an active process that terminates inflammatory …

Cigarette smoke (CS) induces oxidative stress, which disables macrophage function. In this
study, we examined whether Resolvin E1 (RvE1), a pro-resolving mediator known to …

The respiratory epithelium consists of lung sentinel cells, which are the first to contact
inhaled inflammatory insults, including air pollutants, smoke, and microorganisms. To avoid …

Background Inflammation is a key hallmark of ALI and is mediated through ungoverned
cytokine signaling. One such cytokine, interleukin-1beta (IL-1β) has been demonstrated to …

Acute inflammation in the lung is fundamentally important to host defence, but chronic or
excessive inflammation leads to several common respiratory diseases, including asthma …

Increasing evidence suggests that the novel anti-inflammatory and proresolving mediators
such as the resolvins play an important role during inflammation. However, the functions of …

Essential fatty acids can serve as important regulators of inflammation. A new window into
mechanisms for the resolution of inflammation was opened with the identification and …