Exposure to air pollution and other environmental inhalation hazards, such as occupational
exposures to dusts and fumes, aeroallergens, and tobacco smoke, is a significant cause of …

Resolution of inflammation is an active process driven by several new families of
endogenous lipid mediators collectively coined specialized proresolving mediators (SPM) …

Inflammation is associated with the development of diseases characterized by altered
nutrient metabolism. Although an acute inflammatory response is host-protective and …

Fibroblasts, far frombeing merely bystander cells, are known to play a specific role in
inflammation resolution after an acute injury. As the endogenous “braking signal,” resolvins …

Resolvins are generated from omega-3 fatty acids during inflammatory responses in the
lung. These natural mediators interact with specific receptors to decrease lung inflammation …

Resolution is an active process that terminates inflammatory response to maintain health.
Acute inflammation and its timely resolution are important in host response to danger …

Background A variety of inflammatory mediators and effector cells participate together in
acute lung injury, and lead to secondary injury that is due to an inflammatory cascade and …

Background Docosahexaenoic acid (DHA) and DHA-derived lipid mediators have recently
been shown to possess anti-inflammatory and pro-resolving properties. In fact, DHA can …

Acute lung injury (ALI) is a severe illness with excess mortality and no specific therapy.
Protective actions were recently uncovered for docosahexaenoic acid-derived mediators …

The resolution of inflammation is a highly regulated process enacted by endogenous
mediators including specialized pro-resolving lipid mediators (SPMs): the lipoxins, resolvins …