Inappropriate neutrophil activation contributes to the pathogenesis of acute lung injury (ALI).
Apoptosis is essential for removal of neutrophils from inflamed tissues and timely resolution …

Acute inflammation is a host-protective response that is mounted in response to tissue injury
and infection. Initiated and perpetuated by exogenous and endogenous mediators, acute …

Resolution of inflammation is essential. Although supplementation of ω-3 fatty acids is
widely used, their availability at sites of inflammation is not known. To this end, a …

Asthma is a chronic disorder characterized by persistent inflammation of the airways with
mucosal infiltration of eosinophils, T lymphocytes, and mast cells, and release of …

Acute lung injury (ALI), or its more severe form, acute respiratory distress syndrome (ARDS),
is a disease with high mortality and is a serious challenge facing the World Health …

Resolvin E1 (RvE1) is an anti-inflammatory lipid mediator derived from the omega-3 fatty
acid eicosapentaenoic acid (EPA), and strongly acts in the resolution of inflammation. We …

Non-resolving inflammation is the main mechanism of morbidity and mortality among
patients suffering from cystic fibrosis (CF), the most common life-threatening human genetic …

Chronic heart failure (CHF) is characterized by an ongoing nonresolving inflammatory
status, where T lymphocytes seem critical. It has been recently recognized that transition …

The resolution of inflammation is an active and dynamic process critical in maintaining
homeostasis. Newly identified lipid mediators have been recognized as key players during …

The resolution of inflammation has emerged as a critical endogenous process that protects
host tissues from prolonged or excessive inflammation that can become chronic. Failure of …