The goal of this study was to examine the simultaneous effects of mechanical compression
of chondrocytes on mRNA expression and macromolecular synthesis of aggrrecan and type …

The effects of short-and long-term load-controlled compression on the levels of aggrecan
mRNA have been determined. Results show that a compressive stress of 0.1 MPa on bovine …

Articular cartilage responds to its mechanical environment through altered cell metabolism
and matrix synthesis. In this study, isolated articular chondrocytes were cultured in collagen …

Chondrocytes are influenced by mechanical forces to remodel cartilage extracellular matrix.
Previous studies have demonstrated the effects of mechanical forces on changes in …

Static and dynamic compression are known to modulate the metabolism of articular
cartilage. The present study focused on determining the effects of compressive loading on …

This study addressed the hypothesis that duration and magnitude of applied intermittent
hydrostatic pressure (IHP) are critical parameters in regulation of normal human articular …

This study tested the effects of hydrostatic pressure (10 MPa) on adult articular chondrocyte
mRNA and extracellular matrix synthesis in vitro. High density primary cultures of bovine …

Cells of the meniscus are exposed to a wide range of time‐varying mechanical stimuli that
may regulate their metabolic activity in vivo. In this study, the biological response of the …

During skeletal development, growth, and maturation, gradual changes in the material
properties and physical dimensions of cartilage occur under the influence of mechanical …

The effects of compressive stress on the rate of proteoglycan synthesis and release were
determined in bovine articular cartilage from 4–5-month-old animals. Full depth cartilage …