Rationale Atomoxetine, reboxetine and methylphenidate all act at the noradrenaline
transporter (NAT) and atomoxetine and methylphenidate are licensed for the treatment of …

Rationale High levels of impulsivity are a core symptom of psychiatric disorders such as
ADHD, mania, personality disorders and drug addiction. The effectiveness of drugs targeting …

Atomoxetine is a noradrenaline-specific reuptake inhibitor used clinically for the treatment of
childhood and adult attention deficit hyperactivity disorder (ADHD). Studies in human …

Previous studies have shown that drugs which block the reuptake of catecholamine
neurotransmitters improve impulse control in diseases such as attention deficit hyperactivity …

Rationale The ability to detect unpredictable cues can involve stimulus-elicited orienting of
attention (bottom-up processing); however, in many settings, target onset is partially …

Background: Few studies have investigated the effects of conventional attention deficit-
hyperactivity disorder (ADHD) medication in the mouse 5-choice serial reaction time task (5 …

Deficits in attention and response inhibition are apparent across several neurodegenerative
and neuropsychiatric disorders for which current pharmacotherapy is inadequate. The 5 …

Rationale Impulsivity is associated with a number of psychiatric disorders, most notably
attention deficit/hyperactivity disorder (ADHD). Drugs that augment catecholamine function …

Atomoxetine, a noradrenaline reuptake inhibitor (NRI), which is a non-stimulating medicine
that is used for the treatment of patients with attention deficit hyperactivity disorder (ADHD) …

Attention deficit hyperactivity disorder (ADHD) is the most common neurodevelopmental
disorder and is normally treated with either stimulant or non-stimulant medication such as …