Multicentre evaluation of two multiplex PCR platforms for the rapid microbiological investigation of nosocomial pneumonia in UK ICUs: the INHALE WP1 study
VI Enne, A Aydin, R Baldan, DR Owen, H Richardson… - Thorax, 2022 - thorax.bmj.com
Background Culture-based microbiological investigation of hospital-acquired or ventilator-
associated pneumonia (HAP or VAP) is insensitive, with aetiological agents often …
associated pneumonia (HAP or VAP) is insensitive, with aetiological agents often …
[HTML][HTML] Performance of a multiplex PCR pneumonia panel for the identification of respiratory pathogens and the main determinants of resistance from the lower …
SH Lee, SY Ruan, SC Pan, TF Lee, JY Chien… - Journal of Microbiology …, 2019 - Elsevier
Background Timely diagnostic investigation to establish the microbial etiology of pneumonia
is essential to ensure the administration of effective antibiotic therapy to individual patients …
is essential to ensure the administration of effective antibiotic therapy to individual patients …
Comparison of Unyvero P55 Pneumonia Cartridge, in-house PCR and culture for the identification of respiratory pathogens and antibiotic resistance in …
NJ Gadsby, MP McHugh, C Forbes… - European Journal of …, 2019 - Springer
Faster respiratory pathogen detection and antibiotic resistance identification are important in
critical care due to the severity of illness, significant prior antibiotic exposure and infection …
critical care due to the severity of illness, significant prior antibiotic exposure and infection …
16S pan-bacterial PCR can accurately identify patients with ventilator-associated pneumonia
Ventilator-associated pneumonia (VAP) remains a challenge to intensive care units, with
secure diagnosis relying on microbiological cultures that take up to 72 hours to provide a …
secure diagnosis relying on microbiological cultures that take up to 72 hours to provide a …
INHALE: The impact of using FilmArray Pneumonia Panel molecular diagnostics for hospital-acquired and ventilator-associated pneumonia on antimicrobial …
Background Hospital-acquired and ventilator-associated pneumonias (HAP and VAP) are
common in critical care and can be life-threatening. Rapid microbiological diagnostics …
common in critical care and can be life-threatening. Rapid microbiological diagnostics …
Analytical validation of a novel high multiplexing real-time PCR array for the identification of key pathogens causative of bacterial ventilator-associated pneumonia and …
P Bogaerts, S Hamels, R De Mendonça… - Journal of …, 2013 - academic.oup.com
Objectives Rapid diagnosis and appropriate empirical antimicrobial therapy before the
availability of conventional microbiological results is of pivotal importance for the clinical …
availability of conventional microbiological results is of pivotal importance for the clinical …
[HTML][HTML] Evaluation of a multiplex PCR panel for the microbiological diagnosis of pneumonia in hospitalized patients: experience from an academic medical center
IM Zacharioudakis, FN Zervou, Y Dubrovskaya… - International Journal of …, 2021 - Elsevier
Objectives We evaluated the value of BioFire® FilmArray® pneumonia panel in establishing
a microbiological diagnosis of pneumonia. We evaluated opportunities for antimicrobial …
a microbiological diagnosis of pneumonia. We evaluated opportunities for antimicrobial …
Performance evaluation of a PCR panel (FilmArray® Pneumonia Plus) for detection of respiratory bacterial pathogens in respiratory specimens: A systematic review …
AC Moy, A Kimmoun, T Merkling, B Berçot… - … Critical Care & Pain …, 2023 - Elsevier
Background Accuracy and timing of antibiotic therapy remain a challenge for lower
respiratory tract infections. New molecular techniques using Multiplex Polymerase Chain …
respiratory tract infections. New molecular techniques using Multiplex Polymerase Chain …
Rapid syndromic PCR testing in patients with respiratory tract infections reduces time to results and improves microbial yield
S Serigstad, D Markussen, HMS Grewal, M Ebbesen… - Scientific Reports, 2022 - nature.com
Lack of rapid and comprehensive microbiological diagnosis in patients with community
acquired pneumonia (CAP) hampers appropriate antimicrobial therapy. This study evaluates …
acquired pneumonia (CAP) hampers appropriate antimicrobial therapy. This study evaluates …
Potential impact of rapid multiplex PCR on antimicrobial therapy guidance for ventilated hospital-acquired pneumonia in critically ill patients, a prospective …
F Guillotin, C Poulain, B Gaborit, M Bouras… - Frontiers in Cellular …, 2022 - frontiersin.org
Objectives To investigate the potential impact of the syndromic multiplex FilmArray®
Pneumonia plus Panel (FAPP) on the antimicrobial treatment guidance of patients with …
Pneumonia plus Panel (FAPP) on the antimicrobial treatment guidance of patients with …