Abstract Interleukin (IL)-33 is a member of the IL-1 family of cytokines. IL-33 is a nuclear
protein that is also released into the extracellular space, and thus acts as a dual-function …

Abstract Interleukin-33 (IL-33), a newly described member of the IL-1 family, is expressed by
many cell types following pro-inflammatory stimulation and is thought to be released on cell …

Abstract Interleukin (IL)-33 is a cytokine that is released from epithelial and endothelial cells
at barrier surfaces upon tissue stress or damage to operate as an alarmin. IL-33 has been …

Abstract Interleukin-33 (IL-33), a member of the IL-1 family, is an alarmin cytokine with
crucial roles in tissue homeostasis and repair, type 2 immunity, allergic and non-allergic …

Rheumatoid arthritis (RA) is characterized by chronic inflammatory disease, including
synovial proliferation and excessive pro-inflammatory cytokines production, leading to …

In complex disorders such as asthma and allergic disease, the goal for developing disease-
modifying biotherapeutics is to find a target that is a central instigator of immunologic activity …

Abstract Interleukin (IL)-33 is a new member of the IL-1 superfamily of cytokines that is
expressed by mainly stromal cells, such as epithelial and endothelial cells, and its …

Expression of IL-33 is elevated in patients with pulmonary diseases, and full-length (not
proteolytically processed) IL-33 is the predominant form in the lungs in health and disease …

Interleukin-33 (IL-33) belongs to the IL-1 family of cytokines. Whereas IL-1 is processed and
released by live immune cells in response to infection or other triggers, IL-33 is mostly …

Interleukin 33 (IL-33) is an alarmin cytokine from the IL-1 family. IL-33 is localized in the
nucleus and acts there as a gene regulator. Following injury, stress or cell death, it is …