Cholinergic neurotransmission in the hippocampus is involved in cognitive functions,
including learning and memory. Strategies to enhance septohippocampal cholinergic …

Acetylcholine, the first chemical to be identified as a neurotransmitter, is packed in synaptic
vesicles by the activity of VAChT (vesicular acetylcholine transporter). A decrease in VAChT …

An important step for cholinergic transmission involves the vesicular storage of acetylcholine
(ACh), a process mediated by the vesicular acetylcholine transporter (VAChT). In order to …

Cholinergic innervation is extensive throughout the central and peripheral nervous systems.
Among its many roles, the neurotransmitter acetylcholine (ACh) contributes to the regulation …

Rat VAChT cDNA was stably transfected into PC12 cells to generate cell clones
overexpressing different quantities of VAChT protein. Membrane fractions prepared from …

A cholinergic locus has recently been identified consisting of a unique mammalian genomic
arrangement containing the genes for choline acetyltransferase (ChAT) and a putative …

Storage of acetylcholine in synaptic vesicles plays a key role in maintaining cholinergic
function. Here we used mice with a targeted mutation in the vesicular acetylcholine …

The vesicular acetylcholine transporter (VAChT) is a transmembrane protein required, in
cholinergic neurons, for selective storage of acetylcholine into synaptic vesicles. Although …

The vesicular acetylcholine transporter (VAChT) regulates the amount of acetylcholine
stored in synaptic vesicles. However, the mechanisms that control the targeting of VAChT …

The vesicular acetylcholine transporter (VAChT) and choline acetyltransferase (ChAT) are
encoded by genes organized in a single gene locus, and coregulation of the transcription of …