Methods and compositions for co-stimulation of immunological responses to peptide antigens

S Khleif, J Berzofsky - US Patent App. 09/810,310, 2002 - Google Patents
Method for eliciting an immune response in a vertebrate Subject are provided involving
administration of a peptide antigen to the Subject in a coordinated vaccination procedure …

Packaged virus-like particles

M Bachmann, K Schwarz - US Patent App. 10/563,944, 2006 - Google Patents
The present invention is related to the? elds of vaccinology, immunology and medicine. The
invention provides compo sitions and methods for enhancing immunological responses …

Sequential delivery of immunogenic molecules via adenovirus and adeno-associated virus-mediated administrations

JM Wilson - US Patent 8,394,386, 2013 - Google Patents
An immunogenic regimen is provided. The regimen involves sequential administration of a
recombinant adenoviral vector and a recombinant adeno-associated viral vector, each of …

Nucleic acid molecules

M Fotin-Mleczek, K Fiedler, A Kowalczyk… - US Patent …, 2021 - Google Patents
The present invention provides novel artificial nucleic acid molecules encoding at least one
antigenic peptide or protein and at least one additional sequence preferably targeting the …

Epidermal mrna vaccine

M Fotin-Mleczek - US Patent App. 15/749,778, 2020 - Google Patents
The invention concerns the field of genetic vaccination, in particular RNA vaccines. The
present invention provides an mRNA for use in the treatment and/or prevention of a disease …

Methods of augmenting mucosal immunity through systemic priming and mucosal boosting

HCJ Ertl - US Patent 6,210,663, 2001 - Google Patents
A method for inducing and enhancing mammalian mucosal immunity includes the steps of
first administering to a mammal via a non-mucosal route a suitable amount of a priming …

Method for delivery of cosmetic by topical application

P Bernasconi, W Janzen, J Worley - US Patent App. 10/544,790, 2006 - Google Patents
The present invention relates to compositions comprising a baculovirus vector and a
pharmaceutically acceptable carrier to deliver the baculovirus vector onto or into the skin of …

Expression of an exogenous gene in a mammalian cell by use of a non-mammalian DNA virus having an altered coat protein

FM Boyce, JG Barsoum - US Patent 6,190,887, 2001 - Google Patents
Disclosed are methods, nucleic acids, and cells for expressing an exogenous gene in a
mammalian cell, involving introducing into the cell a non-mammalian DNA virus (eg, a …

Generation of an immune response to a pathogen

PL Felgner, JA Wolff, GH Rhodes, RW Malone… - US Patent …, 2004 - Google Patents
A method for delivering an isolated polynucleotide to the interior of a cell in a vertebrate,
comprising the interstitial introduction of an isolated polynucleotide into a tissue of the …

Compositions and methods for delivery of genetic material

RA Carrano, B Wang, DB Weiner - US Patent 5,739,118, 1998 - Google Patents
Methods of introducing genetic material into cells of an individual and compositions and kits
for practicing the same are disclosed. The methods comprise the steps of contacting cells of …