Neuroprotective actions of flavones and flavonols: mechanisms and relationship to flavonoid structural features

F Dajas, AC Juan Andres, A Florencia… - … System Agents in …, 2013 - ingentaconnect.com
Epidemiological studies have shown positive preventive action of flavonoids on
cardiovascular and neurodegenerative events. Among the six groups in which flavonoids …

[HTML][HTML] Peroxisome proliferator-activated receptor γ (PPARγ) mediates the protective effect of quercetin against myocardial ischemia-reperfusion injury via …

X Liu, Z Yu, X Huang, Y Gao, X Wang… - American journal of …, 2016 - ncbi.nlm.nih.gov
Quercetin plays an important role in myocardial ischemia and reperfusion injury (IRI).
However, the underlying mechanism for the protective effect of quercetin is largely unclear …

Dietary flavonoid quercetin stimulates vasorelaxation in aortic vessels

NKH Khoo, CR White, L Pozzo-Miller, F Zhou… - Free Radical Biology …, 2010 - Elsevier
Considerable epidemiological evidence indicates that dietary consumption of moderate
levels of polyphenols decreases both the incidence of cardiovascular disease and the …

Anthocyanins in cardioprotection: A path through mitochondria

J Liobikas, K Skemiene, S Trumbeckaite… - Pharmacological …, 2016 - Elsevier
Constantly growing experimental data from in vitro, in vivo and epidemiological studies
show the great potential of anthocyanin-containing fruit and berry extracts or pure individual …

Dietary polyphenol quercetin protects rat hearts during reperfusion: enhanced antioxidant capacity with chronic treatment.

M İkizler, N Erkasap, S Dernek… - Anatolian Journal of …, 2007 - search.ebscohost.com
Objective: Quercetin is an important member of dietary flavonoid family and widely present
in red wine and Mediterranean diet. The major objective of the this study is to evaluate the …

[HTML][HTML] Quercetin attenuates myocardial ischemia-reperfusion injury via downregulation of the HMGB1-TLR4-NF-κB signaling pathway

LY Dong, F Chen, M Xu, LP Yao, YJ Zhang… - American journal of …, 2018 - ncbi.nlm.nih.gov
The goal of this study was to assess the ability of quercetin (Qu) to protect against
myocardial ischemia-reperfusion injury. Cardiac injury was assessed in the context of global …

Cardioprotection against ischaemia/reperfusion by vitamins C and E plus n−3 fatty acids: molecular mechanisms and potential clinical applications

R Rodrigo, JC Prieto, R Castillo - Clinical science, 2013 - portlandpress.com
The role of oxidative stress in ischaemic heart disease has been thoroughly investigated in
humans. Increased levels of ROS (reactive oxygen species) and RNS (reactive nitrogen …

Cardioprotective effects of dihydroquercetin against ischemia reperfusion injury by inhibiting oxidative stress and endoplasmic reticulum stress-induced apoptosis via …

Z Shu, Y Yang, L Yang, H Jiang, X Yu, Y Wang - Food & function, 2019 - pubs.rsc.org
Dihydroquercetin (DHQ), a dihydroxyflavone, possesses potent antioxidant properties and is
proposed to be useful in the prevention and treatment of cardiovascular disease. In this …

Flavonoid antioxidants

C Rice-Evans - Current medicinal chemistry, 2001 - ingentaconnect.com
In order to ascertain the role of dietary flavonoids as antioxidants in vivo it is necessary to
understand the chemical nature of the absorbed forms in the circulation in vivo and how the …

Molecular mechanisms of cardioprotection by a novel grape seed proanthocyanidin extract

D Bagchi, CK Sen, SD Ray, DK Das, M Bagchi… - Mutation Research …, 2003 - Elsevier
Free radicals and oxidative stress play a crucial role in the pathophysiology of a broad
spectrum of cardiovascular diseases including congestive heart failure, valvular heart …