Analysis of anandamide, an endogenous cannabinoid substance, and of other natural N-acylethanolamines
Recent reports have suggested that N-arachidonoylethanolamine (anandamide) acts as an
endogenous ligand for cannabinoid receptors in mammalian brain. Here we describe …
endogenous ligand for cannabinoid receptors in mammalian brain. Here we describe …
GC/MS Analysis of Anandamide and Quantification of N‐Arachidonoylphosphatidylethanolamides in Various Brain Regions, Spinal Cord, Testis, and Spleen of the …
HYT Yang, F Karoum, C Felder… - Journal of …, 1999 - Wiley Online Library
Anandamide [N‐arachidonoylethanolamide (NAE)] was initially isolated from porcine brain
and proposed as an endogenous ligand for cannabinoid receptors in 1992. Accumulating …
and proposed as an endogenous ligand for cannabinoid receptors in 1992. Accumulating …
N-arachidonoylethanolamine (anandamide), an endogenous cannabinoid receptor ligand, and related lipid molecules in the nervous tissues
T Sugiura, S Kondo, A Sukagawa, T Tonegawa… - Journal of lipid …, 1996 - Elsevier
The effects of N-arachidonoylethanolamine (anandamide) and related compounds on the
binding of [3H] CP55940 to rat brain synaptosomes were examined. Anandamide was …
binding of [3H] CP55940 to rat brain synaptosomes were examined. Anandamide was …
Anandamide and diet: Inclusion of dietary arachidonate and docosahexaenoate leads to increased brain levels of the corresponding N-acylethanolamines in piglets
A Berger, G Crozier, T Bisogno… - Proceedings of the …, 2001 - National Acad Sciences
Endogenous ligands of cannabinoid receptors have been discovered recently and include
some N-acylethanolamines (NAEs; eg, N-arachidonoylethanolamine) and some 2 …
some N-acylethanolamines (NAEs; eg, N-arachidonoylethanolamine) and some 2 …
Anandamide—a new look on fatty acid ethanolamides
EV Berdyshev, E Boichot, V Lagente - Journal of lipid mediators and cell …, 1996 - Elsevier
The first evidence that arachidonoylethanolamide, or anandamide, is the endogenous
compound which specifically binds to and activates brain-type cannabinoid receptors was …
compound which specifically binds to and activates brain-type cannabinoid receptors was …
Brain regional distribution of endocannabinoids: implications for their biosynthesis and biological function
T Bisogno, F Berrendero, G Ambrosino… - Biochemical and …, 1999 - Elsevier
The amounts, in nine different rat brain regions, of the two endocannabinoids, anandamide (
arachidonoylethanolamide, AEA) and 2-arachidonoylglycerol (2-AG), and of the putative …
arachidonoylethanolamide, AEA) and 2-arachidonoylglycerol (2-AG), and of the putative …
Isolation and measurement of the endogenous cannabinoid receptor agonist, anandamide, in brain and peripheral tissues of human and rat
Anandamide (arachidonylethanolamide) is a novel lipid neurotransmitter first isolated from
porcine brain which has been shown to be a functional agonist for the cannabinoid CB1 and …
porcine brain which has been shown to be a functional agonist for the cannabinoid CB1 and …
Occurrence and biosynthesis of endogenous cannabinoid precursor, N-arachidonoyl phosphatidylethanolamine, in rat brain
H Cadas, E di Tomaso, D Piomelli - Journal of Neuroscience, 1997 - Soc Neuroscience
It has been suggested that anandamide (N-arachidonoylethanolamine), an endogenous
cannabinoid substance, may be produced through Ca2+-stimulated hydrolysis of the …
cannabinoid substance, may be produced through Ca2+-stimulated hydrolysis of the …
Astrocytes in culture produce anandamide and other acylethanolamides
Anandamide (arachidonylethanolamide) is an endocannabinoid that belongs to the
acylethanolamide lipid family. It is produced by neurons in a calcium-dependent manner …
acylethanolamide lipid family. It is produced by neurons in a calcium-dependent manner …
Biosynthesis and degradation of anandamide and 2-arachidonoylglycerol and their possible physiological significance
T Sugiura, Y Kobayashi, S Oka, K Waku - Prostaglandins, Leukotrienes and …, 2002 - Elsevier
N-arachidonoylethanolamine (anandamide) was the first endogenous cannabinoid receptor
ligand to be discovered. Dual synthetic pathways for anandamide have been proposed. One …
ligand to be discovered. Dual synthetic pathways for anandamide have been proposed. One …