Many drugs are not being effectively and efficiently delivered using conventional drug
delivery approach to brain or central nervous system (CNS) due to its complexity. The brain …

The treatment of brain disorders is the greatest challenge because of a variety of formidable
obstacles in effective drug delivery and maintaining therapeutic concentrations in the brain …

A major limiting factor for the treatment of central nervous system (CNS) related disorders is
the inability for drug substances to cross the blood-brain barrier. Some medications may …

Alzheimer's disease (AD): AD, a neurodegenerative disorder and a significant cause of
dementia throughout the world mostly affects the older adults but sometimes also seen in …

Blood-brain barrier (BBB) provides restrictions for the transportation of various therapeutic
agents to the brain. Efforts to directly target the brain by olfactory as well as trigeminal nerve …

The treatment of brain disorders is particularly challenging due to the presence of a variety
of formidable obstacles to deliver drugs selectively and effectively to the brain. Blood-brain …

Introduction: Nasal drug delivery that exploits the olfactory and trigeminal neuronal
pathways to deliver drugs to the brain is being widely explored by pharmaceutical …

Treatment of certain central nervous system disorders, including different types of cerebral
malignancies, is limited by traditional oral or systemic administrations of therapeutic drugs …

Nose to brain drug delivery is considered as a viable option to deliver various therapeutic
agents with low cerebral bioavailability bypass blood-brain barrier (BBB). The drug …

Although the global prevalence of neurological disorders such as Parkinson's disease,
Alzheimer's disease, glioblastoma, epilepsy, and multiple sclerosis is steadily increasing …