Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty

L Ferrucci, E Fabbri - Nature Reviews Cardiology, 2018 - nature.com
Most older individuals develop inflammageing, a condition characterized by elevated levels
of blood inflammatory markers that carries high susceptibility to chronic morbidity, disability …

Inflamm-ageing: the role of inflammation in age-dependent cardiovascular disease

L Liberale, F Montecucco, JC Tardif… - European heart …, 2020 - academic.oup.com
The ongoing worldwide increase in life expectancy portends a rising prevalence of age-
related cardiovascular (CV) diseases in the coming decades that demands a deeper …

Inflammation, Aging, and Cardiovascular Disease: JACC Review Topic of the Week

L Liberale, L Badimon, F Montecucco… - Journal of the American …, 2022 - jacc.org
Aging and inflammation both contribute pivotally to cardiovascular (CV) and cerebrovascular
disease, the leading causes of death and disability worldwide. The concept of inflamm-aging …

Inflammation, frailty and cardiovascular disease

P Soysal, F Arik, L Smith, SE Jackson… - Frailty and cardiovascular …, 2020 - Springer
Chronic inflammation, which is called “inflamm-aging”, is characterized by an increased
level of inflammatory cytokines in response to physiological and environmental stressors …

Retracted: chronic inflammation: accelerator of biological aging

B Fougère, E Boulanger, F Nourhashémi… - The Journals of …, 2017 - academic.oup.com
Biological aging is characterized by a chronic low-grade inflammation level. This chronic
phenomenon has been named “inflamm-aging” and is a highly significant risk factor for …

An update on inflamm‐aging: mechanisms, prevention, and treatment

S Xia, X Zhang, S Zheng, R Khanabdali… - Journal of …, 2016 - Wiley Online Library
Inflamm‐aging is a challenging and promising new branch of aging‐related research fields
that includes areas such as immunosenescence. Increasing evidence indicates that inflamm …

Modern concepts in cardiovascular disease: inflamm-aging

YM Puspitasari, S Ministrini, L Schwarz… - Frontiers in cell and …, 2022 - frontiersin.org
The improvements in healthcare services and quality of life result in a longer life expectancy
and a higher number of aged individuals, who are inevitably affected by age-associated …

Source of chronic inflammation in aging

F Sanada, Y Taniyama, J Muratsu, R Otsu… - Frontiers in …, 2018 - frontiersin.org
Aging is a complex process that results from a combination of environmental, genetic, and
epigenetic factors. A chronic pro-inflammatory status is a pervasive feature of aging. This …

Inflammageing in the cardiovascular system: mechanisms, emerging targets, and novel therapeutic strategies

D Liu, G Richardson, FM Benli, C Park… - Clinical …, 2020 - portlandpress.com
In the elderly population, pathological inflammation has been associated with ageing-
associated diseases. The term 'inflammageing', which was used for the first time by …

Chronic low‐grade inflammation in heart failure with preserved ejection fraction

T Mesquita, YN Lin, A Ibrahim - Aging Cell, 2021 - Wiley Online Library
Heart failure (HF) with preserved ejection fraction (HFpEF) is currently the predominant form
of HF with a dramatic increase in risk with age. Low‐grade inflammation, as occurs with …