Molecular strategies and 111in-labelled somatostatin analogues in defining the management of neuroendocrine tumour disease: a new paradigm for surgical …

IM Modlin, M Kidd, T Hinoue, KD Lye, J Murren… - The Surgeon, 2003 - Elsevier
This manuscript provides a gene-chip examination of gastric ECL cell proliferation in an
animal model of neuroendocrine tumour disease. Data that were used to identify molecular …

The use of somatostatin in the diagnosis and treatment of neuroendocrine tumors

DB O'Shea, SR Bloom - Current Opinion in Endocrinology …, 1995 - journals.lww.com
In the past year, there have been major advances in our understanding of the mechanisms
of action of somatostatin. The cloning and characterizing of genes encoding five structurally …

Role of somatostatin analogs in the management of neuroendocrine tumors

F Cirillo - Tumori Journal, 2010 - journals.sagepub.com
Neuroendocrine tumors are rare neoplasms. During the last two decades, somatostatin
analogs, exerting their activity through both receptor binding and enzymatic inhibition …

The role of somatostatin analogues in the treatment of neuroendocrine tumours

S Grozinsky-Glasberg, AB Grossman… - Molecular and cellular …, 2008 - Elsevier
Neuroendocrine tumours belong to a heterogeneous family of neoplasms, originating in
endocrine glands (such as the pituitary, parathyroid or the neuroendocrine adrenal glands) …

[PDF][PDF] Somatostatin analogues in the control of neuroendocrine tumours: efficacy and mechanisms

S Grozinsky-Glasberg, I Shimon… - Endocrine-related …, 2008 - erc.bioscientifica.com
Neuroendocrine tumours (NETs) represent a heterogeneous family of neoplasms, which
may develop from different endocrine glands (such as the pituitary, the parathyroid or the …

Targeted therapy in advanced well‐differentiated neuroendocrine tumors

CP Raut, MH Kulke - The oncologist, 2011 - academic.oup.com
Treatments for advanced neuroendocrine tumors were, until recently, rather limited. Salvage
surgery and liver‐directed therapy both have relatively limited impact, and systemic cytotoxic …

Somatostatin analogues in neuroendocrine tumors

MH Kulke - Journal of the National Comprehensive Cancer …, 2016 - jnccn.org
Patients with advanced neuroendocrine tumors may experience symptoms related to
tumoral secretion of hormones and vasoactive amines as well as symptoms related to tumor …

Is it time to widen the use of somatostatin analogs in neuroendocrine tumors?

KE Öberg - Journal of Clinical Oncology, 2009 - ascopubs.org
Neuroendocrine tumors are considered rare, although their incidence and prevalence have
significantly increased over the last two decades. 1 They are heterogeneous tumors in terms …

Role of somatostatin analogues in the treatment of neuroendocrine tumors

S Narayanan, PL Kunz - Hematology/Oncology Clinics, 2016 - hemonc.theclinics.com
Neuroendocrine tumors (NETs) are epithelial neoplasms with neuroendocrine differentiation
that arise in various anatomic locations throughout the body. The annual incidence of NETs …

Somatostatin analogues in the treatment of neuroendocrine tumors: past, present and future

AK Stueven, A Kayser, C Wetz, H Amthauer… - International journal of …, 2019 - mdpi.com
In recent decades, the incidence of neuroendocrine tumors (NETs) has steadily increased.
Due to the slow-growing nature of these tumors and the lack of early symptoms, most cases …