Abstract Sodium selenite (Na 2 SeO 3) was administered at 2.0 µg selenium (Se) to Swiss
ICR mice six times over a 9-day period by intraperitoneal (ip) injection or by gastric gavage …

INTRODUCTION s IP HAS DISCUSSED,(') selenium supplementation inhibits tumorigenesis
in a variety of organs A and species and under different dietary conditions. The majority of …

The essential trace element selenium retards the growth of certain chemically induced
tumors in animals. The addition of subtoxic amounts of this element in form of selenite to the …

Selenium has been shown to be effective in inhibiting chemically induced or transplantable
tumors. Present information suggests this efficacy depends on the quantity and form …

Epidemiological and animal studies have implicated selenium as a cancer-protective agent.
These reports have generated much enthusiasm for human intervention studies with the …

Experimental studies with rodents indicate that selenium supplementation at levels above
the dietary requirement is capable of protecting against tumorigenesis induced by chemical …

METHODS Eighty female OSU-brown rats were weaned at 35 days of age and didded into
four groups of 20 each. The 40 rats in Groups I and XI were born from parents reared on the …

Abstract Selenium Interactions with Carcinogens. Whanger, PD (1983). Fundam. Appl
Toxicol 3: 424–430. Although selenium was once considered to be a toxic, undesirable and …

The nutritional functions of selenium (Se) are recognized as being due to a number of Se‐
containing proteins. It is not clear, however, whether any of these function in the anti …

In 5 of 6 nondietary tumor-promotion experiments, sodium selenide significantly reduced the
number of tumors in mice. In 2 of these 6 experiments, vitamin E also significantly reduced …