A unified dynamic model for learning, replay, and sharp-wave/ripples
Hippocampal activity is fundamental for episodic memory formation and consolidation.
During phases of rest and sleep, it exhibits sharp-wave/ripple (SPW/R) complexes, which …
During phases of rest and sleep, it exhibits sharp-wave/ripple (SPW/R) complexes, which …
Dorsal and ventral hippocampal sharp-wave ripples activate distinct nucleus accumbens networks
Memories of positive experiences link places, events, and reward outcomes. These
memories recruit interactions between the hippocampus and nucleus accumbens (NAc) …
memories recruit interactions between the hippocampus and nucleus accumbens (NAc) …
Hippocampal sharp-wave ripples in waking and sleeping states
Highlights•Hippocampal SWRs contain neural activity reactivations in both waking and
sleeping.•SWRs in waking and sleeping entail distinct features, particularly replay …
sleeping.•SWRs in waking and sleeping entail distinct features, particularly replay …
Hippocampal replay is not a simple function of experience
Replay of behavioral sequences in the hippocampus during sharp wave ripple complexes
(SWRs) provides a potential mechanism for memory consolidation and the learning of …
(SWRs) provides a potential mechanism for memory consolidation and the learning of …
Hippocampal ripples and memory consolidation
G Girardeau, M Zugaro - Current opinion in neurobiology, 2011 - Elsevier
During slow wave sleep and quiet wakefulness, the hippocampus generates high frequency
field oscillations (ripples) during which pyramidal neurons replay previous waking activity in …
field oscillations (ripples) during which pyramidal neurons replay previous waking activity in …
Hippocampal offline reactivation consolidates recently formed cell assembly patterns during sharp wave-ripples
The ability to reinstate neuronal assemblies representing mnemonic information is thought
to require their consolidation through offline reactivation during sleep/rest. To test this, we …
to require their consolidation through offline reactivation during sleep/rest. To test this, we …
Hippocampal sharp wave/ripples during sleep for consolidation of associative memory
W Ramadan, O Eschenko, SJ Sara - PloS one, 2009 - journals.plos.org
The beneficial effect of sleep on memory has been well-established by extensive research
on humans, but the neurophysiological mechanisms remain a matter of speculation. This …
on humans, but the neurophysiological mechanisms remain a matter of speculation. This …
Coordinated excitation and inhibition of prefrontal ensembles during awake hippocampal sharp-wave ripple events
Interactions between the hippocampus and prefrontal cortex (PFC) are critical for learning
and memory. Hippocampal activity during awake sharp-wave ripple (SWR) events is …
and memory. Hippocampal activity during awake sharp-wave ripple (SWR) events is …
Monosynaptic hippocampal-prefrontal projections contribute to spatial memory consolidation in mice
S Binder, M Mölle, M Lippert, R Bruder… - Journal of …, 2019 - Soc Neuroscience
Time locking between neocortical sleep slow oscillations, thalamo-cortical spindles, and
hippocampal sharp-wave ripples has convincingly been shown to be a key element of …
hippocampal sharp-wave ripples has convincingly been shown to be a key element of …
Hippocampal sharp-wave ripples influence selective activation of the default mode network
The default mode network (DMN) is a commonly observed resting-state network (RSN) that
includes medial temporal, parietal, and prefrontal regions involved in episodic memory [1 …
includes medial temporal, parietal, and prefrontal regions involved in episodic memory [1 …