OBJECTIVE: We wanted to identify the most promising methylation marker candidates for
cervical cancer early detection. METHODS: A systematic literature review was performed in …

OBJECTIVE.: Studies of cervical cancer and its immediate precursor, cervical intraepithelial
neoplasia 3 (CIN3), have identified genes that often show aberrant DNA methylation and …

OBJECTIVE: DNA methylation is an early event in carcinogenesis. Testing for DNA
methylation has potential in cancer screening. The aim of this study was to investigate the …

Aberrant DNA methylation has been observed in cervical cancer; however, most studies
have used non-quantitative approaches to measure DNA methylation. The objective of this …

Multicomponent molecular modifications such as DNA methylation may offer sensitive and
specific cervical intraepithelial neoplasia and cervical cancer biomarkers. In this study, we …

Objectives: To determine methylation status of nine genes, previously described to be
frequently methylated in cervical cancer, in squamous intraepithelial lesions (SIL). Methods …

BACKGROUND: DNA methylation may be used a potential biomarker for detecting cervical
cancer. The authors of this report used quantitative methylation analysis of 4 genes in a full …

Human papillomavirus (HPV) testing has been recently introduced as an alternative to
cytology for cervical cancer screening. However, since most HPV infections clear without …

Testing for DNA methylation has potential in cancer screening. Most previous studies of
DNA methylation in cervical cancer used a candidate gene approach. The aim our study …

Current cervical cancer screening is based on morphological assessment of Pap smears
and associated with significant false negative and false positive results. Previously, we have …