Dear Editor, When treating severe septic shock, vasopressin or epinephrine is generally
added to norepinephrine to increase the mean arterial pressure [1]. However, which of these …

Terlipressin, a long-acting vasopressinergic V1 agonist, is increasingly used to increase
mean arterial blood pressure in the common setting of catecholamine-refractory septic …

Background Critically ill patients often need vasopressors to treat hypotension related to
septic shock and to maintain adequate systemic perfusion. Although the 2017 guidelines of …

Background: The use of low-dose vasopressin as an adjunctive vasopressor in septic shock
is common, but its effect on mortality is unknown. Objective: To determine whether a low …

Objective: We aim to identify the appropriate vasoactive agent in patients with septic shock
who are refractory to optimal doses of norepinephrine. Methods: In this retrospective …

The use of a single biomarker to diagnose or characterize patients or to assess their
response to intervention in a complex disease as sepsis is probably both too simplistic and …

Objective: To summarize literature evaluating vasopressin use, focusing on clinical
controversies regarding initiation, dosing, and discontinuation and interaction of vasopressin …

Background The effect of norepinephrine in patients with septic shock remains controversial.
We conducted a meta-analysis to compare the mortality rates and benefits of norepinephrine …

Cardiovascular failure is one of the central therapeutic problems in patients with severe
infection. Although norepinephrine is a potent and, in most cases, highly effective …

Purpose The metabolic and circulatory disturbances in patients with septic shock results in a
high mortality rate. There is a lack of high-level evidence on the optimal approach. We …