Stearoyl‐C o A desaturase‐1 (SCD 1) is an endoplasmic reticulum anchored enzyme
catalyzing the synthesis of monounsaturated fatty acids, mainly palmytoleyl‐C o A and oleyl …

Background Intra-tumoral heterogeneity (ITH) is a distinguished hallmark of cancer, and
cancer stem cells (CSCs) contribute to this malignant characteristic. Therefore, it is of great …

Background More than 80% of intestinal neoplasia is associated with the adenomatous
polyposis coli (APC) mutation. Doublecortin-like kinase 1 (Dclk1), a kinase protein, is …

Cancer cells undergo comprehensive metabolic reprogramming to meet the increased
requirements of energy and building blocks for proliferation. Lipin‐1, a phosphatidic acid …

Fatty acid synthase (FASN) is a key lipogenic enzyme for de novo fatty acid biosynthesis and
a druggable metabolic oncoprotein that is activated in most human cancers. We evaluated …

From laboratory animal studies of genistein and human chorionic gonadotropin, induction of
mammary gland differentiation could be a mechanism for chemoprevention. Besides …

Lipid metabolism is frequently perturbed in cancers, but the underlying mechanism is
unclear. We present comprehensive evidence that oncogene MYC, in collaboration with …

Fatty acid synthase (FASN), the key metabolic enzyme of de novo lipogenesis, provides
proliferative and metastatic capacity directly to cancer cells have been described. However …

Breast cancer stem cells (BCSCs) are intrinsically chemoresistant and capable of self-
renewal. Following chemotherapy, patients can develop minimal residual disease due to …

Breast cancer (BC) is an important cause of female cancer‐related death. It has recently
been demonstrated that metabolic disorders including lipid metabolism are a hallmark of …