EGFR mutation-guided use of afatinib, erlotinib and gefitinib for advanced non-small-cell lung cancer in Hong Kong–A cost-effectiveness analysis

JHS You, WCS Cho, W Ming, Y Li, C Kwan, K Au… - PLoS …, 2021 - journals.plos.org
Introduction Tyrosine kinase inhibitors (TKIs) therapy targets at epidermal growth factor
receptor (EGFR) gene mutations in non-small-cell lung cancer (NSCLC). We aimed to …

Cost-effectiveness of afatinib, gefitinib, erlotinib and pemetrexed-based chemotherapy as first-line treatments for advanced non-small cell lung cancer in China

X Gu, Q Zhang, YB Chu, YY Zhao, YJ Zhang, D Kuo… - Lung Cancer, 2019 - Elsevier
Purpose Tyrosine kinase inhibitors (TKI) of the epidermal growth factor receptor (EGFR) are
becoming the standard treatments for Chinese patients with advanced non-small cell lung …

Cost-effectiveness analysis of EGFR mutation testing and afatinib versus gemcitabine-cisplatin as first-line therapy for advanced non-small-cell lung cancer in China

R You, J Liu, DBC Wu, XY Qian, B Lyu… - Cancer management …, 2019 - Taylor & Francis
Objective The purpose of this study was to evaluate the cost-effectiveness of the combined
use of afatinib and epidermal growth factor receptor (EGFR) testing versus gemcitabine …

Cost-effectiveness analysis of afatinib, erlotinib, and gefitinib as first-line treatments for EGFR mutation-positive non-small-cell lung cancer in Ontario, Canada

YJ Kim, M Oremus, HH Chen, T McFarlane… - …, 2021 - Springer
Objective The objective of this study was to compare the cost effectiveness of first-line
epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) for the treatment of …

Cost-effectiveness analysis of first and second-generation EGFR tyrosine kinase inhibitors as first line of treatment for patients with NSCLC harboring EGFR mutations

O Arrieta, R Catalán, S Guzmán-Vazquez, F Barrón… - BMC cancer, 2020 - Springer
Abstract Background Tyrosine-kinase inhibitors (TKIs) have become the cornerstone
treatment of patients with non-small cell lung cancer that harbor oncogenic EGFR mutations …

First-or second-generation epidermal growth factor receptor tyrosine kinase inhibitors in a large, real-world cohort of patients with non-small cell lung cancer

ACC Huang, CH Huang, JS Ju… - Therapeutic …, 2021 - journals.sagepub.com
Background: There are limited comparisons of first-and second-generation EGFR tyrosine
kinase inhibitors (TKIs) in large, real-world cohorts of non-small cell lung cancer (NSCLC) …

Cost effectiveness analysis of afatinib versus pemetrexed-cisplatin for first-line treatment of locally advanced or metastatic EGFR mutation positive non-small-cell lung …

PT Tan, MIA Aziz, F Pearce, WT Lim, DBC Wu, K Ng - BMC cancer, 2018 - Springer
Background Non-small-cell lung cancer (NSCLC) accounts for 85% of all lung cancers and
is associated with a poor prognosis. Afatinib is an irreversible ErbB family blocker …

The efficacy of first-line tyrosine kinase inhibitors combined with co-medications in Asian patients with EGFR mutation non-small cell lung cancer

VYF Su, KY Yang, TY Huang, CC Hsu, YM Chen… - Scientific reports, 2020 - nature.com
The real-world efficacy of epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors
(TKIs) in patients with advanced non-small cell lung cancer (NSCLC) harboring EGFR …

[HTML][HTML] Cost-effectiveness analysis of afatinib versus gefitinib for first-line treatment of advanced EGFR-mutated advanced non–small cell lung cancers

C Chouaid, L Luciani, K LeLay, P Do… - Journal of thoracic …, 2017 - Elsevier
Abstract Introduction The irreversible ErbB family blocker afatinib and the reversible EGFR
tyrosine kinase inhibitor gefitinib were compared in the multicenter, international …

Real-world outcomes of first-and second-generation tyrosine kinase inhibitors first-line in patients with epidermal growth factor receptor mutation-positive non-small …

WW Ng, CC Lin, CY Cheng, JS Jiang, SJ Kao, DY Yeh - Plos one, 2021 - journals.plos.org
The sequencing of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs)
in patients with EGFR mutation-positive (EGFRm+) non-small cell lung cancer (NSCLC) …