Glucagon-like peptide-1: a focus on neurodegenerative diseases
M Grieco, A Giorgi, MC Gentile, M d'Erme… - Frontiers in …, 2019 - frontiersin.org
Diabetes mellitus is one of the major risk factors for cognitive dysfunction. The pathogenesis
of brain impairment caused by chronic hyperglycemia is complex and includes …
of brain impairment caused by chronic hyperglycemia is complex and includes …
The role of glucagon-like peptide 1 (GLP1) in type 3 diabetes: GLP-1 controls insulin resistance, neuroinflammation and neurogenesis in the brain
CS Bae, J Song - International journal of molecular sciences, 2017 - mdpi.com
Alzheimer's disease (AD), characterized by the aggregation of amyloid-β (Aβ) protein and
neuroinflammation, is the most common neurodegenerative disease globally. Previous …
neuroinflammation, is the most common neurodegenerative disease globally. Previous …
Glucagon like peptide-1 (GLP-1) likes Alzheimer's disease
IY Simsir, UE Soyaltin, S Cetinkalp - Diabetes & Metabolic Syndrome …, 2018 - Elsevier
Abstract Glucagon-like peptide-1 (GLP-1) is a 30 amino acid long peptide hormone derived
from the proglucagon gene and secreted in the distal small intestine when food enters the …
from the proglucagon gene and secreted in the distal small intestine when food enters the …
Neuroprotective and neurotrophic actions of glucagon‐like peptide‐1: an emerging opportunity to treat neurodegenerative and cerebrovascular disorders
I Salcedo, D Tweedie, Y Li… - British journal of …, 2012 - Wiley Online Library
Like type‐2 diabetes mellitus (T2DM), neurodegenerative disorders and stroke are an ever
increasing, health, social and economic burden for developed Westernized countries. Age is …
increasing, health, social and economic burden for developed Westernized countries. Age is …
GLP-1's role in neuroprotection: a systematic review
D Erbil, CY Eren, C Demirel, MU Küçüker, I Solaroğlu… - Brain injury, 2019 - Taylor & Francis
ABSTRACT Glucagon-like peptide 1 (GLP-1) is a target for treatment of diabetes; however,
its function in the brain is not well studied. In this systematic review, we aimed to analyze the …
its function in the brain is not well studied. In this systematic review, we aimed to analyze the …
The neuroprotective effects of glucagon-like peptide 1 in Alzheimer's and Parkinson's disease: An in-depth review
N Reich, C Hölscher - Frontiers in neuroscience, 2022 - frontiersin.org
Currently, there is no disease-modifying treatment available for Alzheimer's and Parkinson's
disease (AD and PD) and that includes the highly controversial approval of the Aβ-targeting …
disease (AD and PD) and that includes the highly controversial approval of the Aβ-targeting …
Glucagon-like peptide-1 and the central/peripheral nervous system: crosstalk in diabetes
G Muscogiuri, RA DeFronzo, A Gastaldelli… - Trends in Endocrinology …, 2017 - cell.com
Glucagon-like peptide-1 (GLP-1) is released in response to meals and exerts important roles
in the maintenance of normal glucose homeostasis. GLP-1 is also important in the regulation …
in the maintenance of normal glucose homeostasis. GLP-1 is also important in the regulation …
The role of glucagon-like peptide-1 receptor agonists (GLP-1 RA) in diabetes-related neurodegenerative diseases
D Cheng, S Yang, X Zhao, G Wang - Drug design, development …, 2023 - Taylor & Francis
Recent clinical guidelines have emphasized the importance of screening for cognitive
impairment in older adults with diabetes, however, there is still a lack of understanding about …
impairment in older adults with diabetes, however, there is still a lack of understanding about …
Potential role of glucagon-like peptide-1 (GLP-1) in neuroprotection
C Hölscher - CNS drugs, 2012 - Springer
The current understanding of neurodegenerative processes in sporadic diseases such as
Alzheimer's disease (AD), Parkinson's disease (PD) or multiple sclerosis is very limited …
Alzheimer's disease (AD), Parkinson's disease (PD) or multiple sclerosis is very limited …
Neuroprotective mechanisms of glucagon-like peptide-1-based therapies in ischemic stroke: an update based on preclinical research
X Yang, Q Qiang, N Li, P Feng, W Wei… - Frontiers in …, 2022 - frontiersin.org
The public and social health burdens of ischemic stroke have been increasing worldwide.
Hyperglycemia leads to a greater risk of stroke. This increased risk is commonly seen …
Hyperglycemia leads to a greater risk of stroke. This increased risk is commonly seen …