Our understanding of albuterol nebulization driven by helium-oxygen mixture (heliox) has
matured with recent advances in clinical therapy, delivery systems, and understanding of …

BACKGROUND: Whereas high-flow nasal cannula (HFNC) oxygen therapy is increasingly
used in patients with exacerbation of COPD, the effectiveness of β 2 agonist nebulization …

Expiratory airway collapse is a characteristic feature in patients with chronic obstructive
pulmonary disease (COPD). We hypothesized that this collapse might mask the effects of …

To compare the deposition patterns of heliox-driven and air-driven radiolabeled
bronchodilator aerosol, a prospective randomized study was undertaken at the Ben Taub …

Study objectives Despite the widespread use of short-acting, inhaled β 2-agonists in acute
exacerbations of COPD (AECOPDs), little is known about their optimal dose. The aims of this …

Objective To evaluate, by systematic review, the efficacy of heliox on respiratory mechanics
and outcomes in patients with acute asthma. Methods The search strategy included …

Objectives: To determine and define the beneficial effects of heliox‐driven albuterol therapy
on severe asthma exacerbation and clinical factors that affect greater response. Methods …

In this issue of CHEST (see page 891), Carlos and Gustavo Rodrigo review studies that
examine the clinical efficacy of heliox for the management of patients with asthma. To …

Background and objective Patients with COPD exhibit increased inspiratory work and
dyspnea due to dynamic hyperinflation caused by expiratory flow limitation. Helium-oxygen …

Background The relationship between patient-reported symptoms and objective measures
of lung function is poorly understood. Aim To determine the association between …