Effects of the neuropeptide Y Y2 receptor antagonist BIIE0246 on sympathetic transmitter release in the pig in vivo

RE Malmström, JO Lundberg, E Weitzberg - … -Schmiedeberg's archives of …, 2002 - Springer
This study investigated the effects of BIIE0246, a novel neuropeptide Y (NPY) Y 2 receptor
antagonist, on renal sympathetic nerve-evoked release of noradrenaline and NPY-like …

Autoinhibitory function of the sympathetic prejunctional neuropeptide Y Y2 receptor evidenced by BIIE0246

RE Malmström, JON Lundberg, E Weitzberg - European journal of …, 2002 - Elsevier
The significance of neuropeptide Y Y2 receptors in sympathetic nonadrenergic transmission
was investigated using the novel selective antagonist BIIE0246 ((S)-N2-[[1-[2-[4-[(R, S)-5, 11 …

Inhibition of sympathetic vasoconstriction in pigs in vivo by the neuropeptide Y‐Y1 receptor antagonist BIBP 3226

JM Lundberg, A Modin - British journal of pharmacology, 1995 - Wiley Online Library
1 Recently, a potent non‐peptide antagonist of neuropeptide Y (NPY)‐Y1 receptors has
been developed. In this study, the selectivity of this compound, BIBP 3226, as a functional …

The neuropeptide Y (NPY) Y1 receptor antagonist BIBP 3226: effects on vascular responses to exogenous and endogenous NPY in the pig in vivo

RE Malmström, KC Balmér… - British journal of …, 1997 - Wiley Online Library
The antagonistic effects of the neuropeptide Y (NPY) Y1 receptor antagonist BIBP 3226 on
equally prominent vascular responses evoked by sympathetic nerve stimulation and …

SR 120107A antagonizes neuropeptide Y Y1 receptor mediated sympathetic vasoconstriction in pigs in vivo

RE Malmström, A Modin, JM Lundberg - European journal of pharmacology, 1996 - Elsevier
The effects of the neuropeptide Y Y1 receptor antagonist SR 120107A (1-[2-[2-(2-
naphtylsulfamoyl)-3-phenylpropionamido]-3-[4-[N-[4-(dimethylaminomethyl)-cis …

Pharmacology of H 394/84, a dihydropyridine neuropeptide Y Y1 receptor antagonist, in vivo

RE Malmström, KC Balmér, J Weilitz… - European journal of …, 2001 - Elsevier
The object of the present paper was to investigate the in vivo pharmacological profile of the
dihydropyridine neuropeptide Y Y1 receptor antagonist 1, 4-Dihydro-4-[3-[[[[3-[spiro (indene …

In vivo characterization of the novel neuropeptide Y Y1 receptor antagonist H 409/22

RE Malmström, A Alexandersson… - Journal of …, 2000 - journals.lww.com
We studied the effects of the novel neuropeptide Y (NPY) Y 1 receptor antagonist H 409/22,
and its inactive enantiomer H 510/45, on vascular responses evoked by endogenous and …

Pharmacological characterization of neuropeptide Y and noradrenaline mechanisms in sympathetic control of pig spleen

JM Lundberg, A Rudehill, A Sollevi - European journal of pharmacology, 1989 - Elsevier
The mechanism underlying the functional effects of neuropeptide Y (NPY)-like
immunoreactivity (LI) and noradrenaline (NA) and their release evoked by nerve stimulation …

Effects of the neuropeptide YY1 receptor antagonist SR 120107A on sympathetic vascular control in pigs in vivo

RE Malmström, JM Lundberg - Naunyn-Schmiedeberg's archives of …, 1996 - Springer
The possible involvement of neuropeptide Y in sympathetic vasoconstriction in various
vascular beds in anesthetized pigs in vivo was studied using the neuropeptide YY 1 receptor …

Prejunctional regulation of reserpine-resistant sympathetic vasoconstriction and release of neuropeptide Y in the pig

A Modin, J Pernow, JM Lundberg - Journal of the autonomic nervous …, 1996 - Elsevier
The prejunctional regulation of non-adrenergic sympathetic vasoconstriction and release of
neuropeptide Y (NPY) was investigated in vivo. In reserpinized pigs (with depleted …