[HTML][HTML] A spatiotemporal profile of in vivo cerebral blood flow changes following intranasal oxytocin in humans

Y Paloyelis, OM Doyle, FO Zelaya, S Maltezos… - Biological …, 2016 - Elsevier
Background Animal and human studies highlight the role of oxytocin in social cognition and
behavior and the potential of intranasal oxytocin (IN-OT) to treat social impairment in …

Aerosolized oxytocin increases cerebrospinal fluid oxytocin in rhesus macaques

ME Modi, F Connor-Stroud, R Landgraf… - …, 2014 - Elsevier
Intranasal (IN) administration is a widely used method for examining the effect of oxytocin
(OT) on social behavior and cognition in healthy subjects and psychiatric populations. IN-OT …

[HTML][HTML] Chronic and acute intranasal oxytocin produce divergent social effects in mice

H Huang, C Michetti, M Busnelli, F Manago… - …, 2014 - nature.com
Intranasal administration of oxytocin (OXT) might be a promising new adjunctive therapy for
mental disorders characterized by social behavioral alterations such as autism and …

Oxytocin and the social brain: neural mechanisms and perspectives in human research

M Kanat, M Heinrichs, G Domes - Brain research, 2014 - Elsevier
The present paper summarizes functional imaging studies investigating the effects of
intranasal oxytocin (OT) on brain responses to social stimuli. We aim to integrate previous …

[HTML][HTML] CSF and blood oxytocin concentration changes following intranasal delivery in macaque

O Dal Monte, PL Noble, J Turchi, A Cummins… - PloS one, 2014 - journals.plos.org
Oxytocin (OT) in the central nervous system (CNS) influences social cognition and behavior,
making it a candidate for treating clinical disorders such as schizophrenia and autism …

Neurochemical evidence for differential effects of acute and repeated oxytocin administration

S Benner, Y Aoki, T Watanabe, N Endo, O Abe… - Molecular …, 2021 - nature.com
A discrepancy in oxytocin's behavioral effects between acute and repeated administrations
indicates distinct underlying neurobiological mechanisms. The current study employed a …

Intranasal oxytocin selectively attenuates rhesus monkeys' attention to negative facial expressions

LA Parr, M Modi, E Siebert, LJ Young - Psychoneuroendocrinology, 2013 - Elsevier
Intranasal oxytocin (IN-OT) modulates social perception and cognition in humans and could
be an effective pharmacotherapy for treating social impairments associated with …

[HTML][HTML] Oxytocin treatment attenuates amygdala activity in autism: a treatment-mechanism study with long-term follow-up

S Bernaerts, B Boets, J Steyaert, N Wenderoth… - Translational …, 2020 - nature.com
Intranasal administration of the neuropeptide oxytocin (IN-OT) is increasingly considered as
a potential treatment for targeting the core symptoms of autism spectrum disorder (ASD), but …

[HTML][HTML] Intranasal oxytocin and vasopressin modulate divergent brainwide functional substrates

A Galbusera, A De Felice, S Girardi… - …, 2017 - nature.com
The neuropeptides oxytocin (OXT) and vasopressin (AVP) have been identified as
modulators of emotional social behaviors and associated with neuropsychiatric disorders …

Oxytocin induces long-lasting adaptations within amygdala circuitry in autism: a treatment-mechanism study with randomized placebo-controlled design

K Alaerts, S Bernaerts, J Prinsen, C Dillen… - …, 2020 - nature.com
Intranasal administration of the neuropeptide oxytocin (IN-OT) is increasingly explored as a
potential treatment for targeting the core symptoms of autism spectrum disorder (ASD). To …